The University of Sydney  - Home

MANGO: Magnetic resonance imaging of hypoxia for radiation treatment guidance in glioblastoma multiforme

Using imaging biomarkers of hypoxia to improve diagnostic and prognostics in GBM management.

This study is designed to evaluate the role of Oxygen Enhanced (OE) Magnetic resonance imaging (MRI) and Blood Oxygenation Level Dependent (BOLD) MRI in detecting regions of hypoxic tumour and to evaluate their use as imaging methods to selectively deliver targeted radiotherapy to regions of aggressive disease.

Trial information page: https://clinicaltrials.gov/study/NCT05500612

Trial protocol paper: https://pubmed.ncbi.nlm.nih.gov/38192626/