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2025

AUTHORS TITLE PUBLICATION DOI
Hood S, Newall M, Butler P, O’Brien R, et al. First linac-mounted photon counting detector for image guided radiotherapy: Planar image quality characterization Med Phys. 2025 Feb;52(2):1159-1171 10.1002/mp.17540
Wilding-McBride D, Lim J, Byrne H, O’Brien R. CT ventilation images produced by a 3D neural network show improvement over the Jacobian and HU DIR-based methods to predict quantized lung function Med Phys. 2025 Feb;52(2):889-898 10.1002/mp.17532
Dillon O, Lau B, Vinod SK, Keall PJ, et al. Real-time spatiotemporal optimization during imaging Commun Eng. 2025 Mar 31;4(1):61 10.1038/s44172-025-00391-9
Lassen ML, Kertész H, Rausch I, Panin V, et al. Positron Range Correction Helps Enhance the Image Quality of Cardiac 82Rb PET/CT J Nucl Med. 2025 Mar 3;66(3):466-472 10.2967/jnumed.124.267855
Hindmarsh J, Crowe S, Johnson J, Sengupta C, et al. A dosimetric comparison of helical tomotherapy treatment delivery with real-time adaption and no motion correction Phys Imaging Radiat Oncol. 2025 Mar 5;34:100741 10.1016/j.phro.2025.100741
Trada Y, Lee MT, Jameson MG, Chlap P, et al. Mid-treatment changes in intra-tumoural metabolic heterogeneity correlate to outcomes in oropharyngeal squamous cell carcinoma patients EJNMMI Res. 2025 Apr 1;15(1):31 10.1186/s13550-025-01226-6

 

2024

AUTHORS TITLE PUBLICATION DOI
Abdel-Wahab M, Coleman CN, Eriksen JG, Lee P, Kraus R, Harsdorf E, et al. Addressing challenges in low-income and middle-income countries through novel radiotherapy research opportunities Lancet Oncol 10.1016/s1470-2045(24)00038-x
Akwo JD, Trieu PDY, Barron ML, Reynolds T, Lewis SJ Access to prior screening mammograms affects the specificity but not sensitivity of radiologists’ performance Clin Radiol 10.1016/j.crad.2024.09.007
Akwo JD, Trieu PDY, Barron ML, Reynolds T, Lewis SJ Does access to prior mammograms improve the performance of radiographers in interpreting screening mammograms? Radiography (Lond) 10.1016/j.radi.2024.11.025
Ben Bouchta Y, Gardner M, Sengupta C, Johnson J, Keall P The Remove-the-Mask Open-Source head and neck Surface-Guided radiation therapy system Phys Imaging Radiat Oncol 10.1016/j.phro.2024.100541
Byrne HL, Steiner E, Booth J, Lamoury G, Morgia M, et al. Prospective Randomized Trial Comparing 2 Devices for Deep Inspiration Breath Hold Management in Breast Radiation Therapy: Results of the BRAVEHeart Trial Adv Radiat Oncol 10.1016/j.adro.2024.101572
Chin V, Chlap P, Finnegan R, Hau E, Ong A, Ma X, et al. Cardiac Substructure Dose and Survival in Stereotactic Radiotherapy for Lung Cancer: Results of the Multi-Centre SSBROC Trial Clin Oncol (R Coll Radiol) 10.1016/j.clon.2024.07.005
Chin V, Finnegan RN, Chlap P, Holloway L, Thwaites DI, et al. Dosimetric Impact of Delineation and Motion Uncertainties on the Heart and Substructures in Lung Cancer Radiotherapy Clin Oncol (R Coll Radiol) 10.1016/j.clon.2024.04.002
Chin V, Finnegan RN, Keall P, Otton J, Delaney GP, Vinod SK Overview of cardiac toxicity from radiation therapy J Med Imaging Radiat Oncol 10.1111/1754-9485.13757
Choi S, Brighi C, Long S Dynamic contrast enhanced high field magnetic resonance imaging for canine primary intracranial neoplasia Front Vet Sci 10.3389/fvets.2024.1468831
Gardner M, Dillon O, Byrne H, Keall P, O’Brien R Data-driven rapid 4D cone-beam CT reconstruction for new generation linacs Phys Med Biol 10.1088/1361-6560/ad780a
Gardner M, Finnegan RN, Dillon O, Chin V, Reynolds T, Keall PJ Investigation of cardiac substructure automatic segmentation methods on synthetically generated 4D cone-beam CT images Med Phys 10.1002/mp.17596
Grover J, Liu P, Dong B, Shan S, Whelan B, Keall P, Waddington DEJ Super-resolution neural networks improve the spatiotemporal resolution of adaptive MRI-guided radiation therapy Commun Med (Lond) 10.1038/s43856-024-00489-9
Hewson EA, Dillon O, Poulsen PR, Booth JT, Keall PJ Six-degrees-of-freedom pelvic bone monitoring on 2D kV intrafraction images to enable multi-target tracking for locally advanced prostate cancer Med Phys 10.1002/mp.17465
Hindley N, DeVience SJ, Zhang E, Cheng LL, Rosen MS A statistical learning framework for mapping indirect measurements of ergodic systems to emergent properties Journal of Magnetic Resonance Open 10.1016/j.jmro.2024.100151
Hood S, Newall M, Butler P, O’Brien R, Petasecca M, et al. First linac-mounted photon counting detector for image guided radiotherapy: Planar image quality characterization Med Phys 10.1002/mp.17540
Huang X, Field M, Vinod S, Ball H, Batumalai V, Keall P, Holloway L Radiotherapy protocol compliance in routine clinical practice for patients with stages I-III non-small-cell lung cancer J Med Imaging Radiat Oncol 10.1111/1754-9485.13727
Klucznik KA, Ravkilde T, Skouboe S, Møller DS, Hokland SB, et al. Quantifying dose perturbations in high-risk prostate radiotherapy due to translational and rotational motion of prostate and pelvic lymph nodes Med Phys 10.1002/mp.17366
Lau BKF, Dillon O, Vinod SK, O’Brien RT, Reynolds T Faster and lower dose imaging: evaluating adaptive, constant gantry velocity and angular separation in fast low-dose 4D cone beam CT imaging Med Phys 10.1002/mp.16585
Lombardo E, Dhont J, Page D, Garibaldi C, Künzel LA, et al. Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects Radiother Oncol 10.1016/j.radonc.2023.109970
Ma YQ, Reynolds T, Ehtiati T, Weiss C, Hong K, et al. Fully automatic online geometric calibration for non-circular cone-beam CT orbits using fiducials with unknown placement Med Phys 10.1002/mp.17041
Madden L, Ahmed A, Stewart M, Chrystall D, Mylonas A, et al. CBCT-DRRs superior to CT-DRRs for target-tracking applications for pancreatic SBRT Biomed Phys Eng Express 10.1088/2057-1976/ad3bb9
Plant N, Mylonas A, Sengupta C, Nguyen DT, Silvester S, et al. Radio-opaque contrast agents for liver cancer targeting with KIM during radiation therapy (ROCK-RT): an observational feasibility study Radiat Oncol 10.1186/s13014-024-02524-4
Reynolds T, Dillon O, Ma Y, Hindley N, Stayman JW, Bazalova-Carter M Investigating 4D respiratory cone-beam CT imaging for thoracic interventions on robotic C-arm systems: a deformable phantom study Phys Eng Sci Med 10.1007/s13246-024-01491-0
Reynolds T, Ma Y, Kanawati A, Dillon O, Baer K, Gang G, Stayman J Universal non-circular cone beam CT orbits for metal artifact reduction imaging during image-guided procedures Sci Rep 10.1038/s41598-024-77964-9
Sengupta C, Nguyen DT, Li Y, Hewson E, Ball H, et al. The TROG 15.01 stereotactic prostate adaptive radiotherapy utilizing kilovoltage intrafraction monitoring (SPARK) clinical trial database Med Phys 10.1002/mp.17529
Sengupta C, Nguyen DT, Moodie T, Mason D, Luo J, et al. The first clinical implementation of real-time 6 degree-of-freedom image-guided radiotherapy for liver SABR patients Radiother Oncol 10.1016/j.radonc.2023.110031
Shan S, Gao Y, Waddington D, Chen H, Whelan B, et al. Image Reconstruction With B₀ Inhomogeneity Using a Deep Unrolled Network on an Open-Bore MRI-Linac IEEE Transactions on Instrumentation and Measurement 10.1109/TIM.2024.3481545
Shen S, Koonjoo N, Boele T, Lu J, Waddington DEJ, et al. Enhancing organ and vascular contrast in preclinical ultra-low field MRI using superparamagnetic iron oxide nanoparticles Commun Biol 10.1038/s42003-024-06884-1
Whelan BM, Liu PZY, Shan S, Waddington DEJ, Dong B, et al. Open-source hardware and software for the measurement, characterization, reporting, and correction of geometric distortion in MRI Med Phys 10.1002/mp.17342

2023

AUTHORS TITLE PUBLICATION DOI
Ahmed AM, Gargett M, Madden L, Mylonas A, Chrystall D, Brown R, Briggs A, Nguyen DT, Keall P, Kneebone A, Hruby G, Booth J Evaluation of deep learning based implanted fiducial markers tracking in pancreatic cancer patients Biomed Phys Eng Express 9(3) 10.1088/2057-1976/acb550
Blake SJ, Dillon O, Byrne HL, O’Brien RT Thoracic motion-compensated cone-beam computed tomography in under 20 seconds on a fast-rotating linac: A simulation study J Appl Clin Med Phys 24(3): e13909 10.1002/acm2.13909
Brighi C, Puttick S, Woods A, Keall P, Tooney PA, Waddington DEJ, Sproule V, Rose S, Fay M Comparison between [(68)Ga]Ga-PSMA-617 and [(18)F]FET PET as Imaging Biomarkers in Adult Recurrent Glioblastoma Int J Mol Sci 24(22) 10.3390/ijms242216208
Brighi C, Waddington D, Keall P, Booth J, O’Brien K, Silvester S, Parkinson J, Mueller M, Yim J, Bailey D, Back M, Drummond J The MANGO study: A prospective investigation of oxygen enhanced and blood-oxygen level dependent MRI as imaging biomarkers of hypoxia in glioblastoma Frontier Oncol 13 10.3389/fonc.2023.1306164
Byrne HL, Steiner E, Booth J, Lamoury G, Morgia M, Richardson K, Ambrose L, Makhija K, Stanton C, Zwan B, Bromley R, Atyeo J, Silvester S, Plant N, Keall P BRAVEHeart: a randomised trial comparing the accuracy of Breathe Well and RPM for deep inspiration breath hold breast cancer radiotherapy Trials 24(1): 132 10.1186/s13063-023-07072-y
Capaldi DPI, Keall PJ, Nano TF Motion Management and Image-Guided Radiation Therapy Artificial Intelligence in Radiation Oncology and Biomedical Physics. G. Valdes and L. Xing. Boca Raton, CRC Press 10.1201/9781003094333
Carr MA, Gargett M, Stanton C, Zwan B, Byrne HL, Booth JT A method for beam’s eye view breath-hold monitoring during breast volumetric modulated arc therapy Phys Imaging Radiat Oncol 25: 100419 10.1016/j.phro.2023.100419
Chrystall D, Mylonas A, Hewson E, Martin J, Keall P, Booth J, Nguyen DT Deep learning enables MV-based real-time image guided radiation therapy for prostate cancer patients Phys Med Biol 68(9) 10.1088/1361-6560/acc77c
Debrot E, Liu P, Gardner M, Heng SM, Chan CH, Corde S, Downes S, Jackson M, Keall P Nano X Image Guidance in radiation therapy: feasibility study protocol for cone beam computed tomography imaging with gravity-induced motion Pilot Feasibility Stud 9(1): 95 10.1186/s40814-023-01340-z
Dillon O, Reynolds T, O’Brien RT X-ray source arrays for volumetric imaging during radiotherapy treatment Sci Rep 13(1): 9776 10.1038/s41598-023-36708-x
Gardner M, Bouchta YB, Mylonas A, Mueller M, Cheng C, Chlap P, Finnegan R, Sykes J, Keall PJ, Nguyen DT Realistic CT data augmentation for accurate deep-learning based segmentation of head and neck tumors in kV images acquired during radiation therapy Med Phys 50(7): 4206-4219 10.1002/mp.16388
Gardner M, Bouchta YB, Sykes J, Keall PJ A kinematics-based method for creating deformed patient-derived head and neck CT scans Annu Int Conf IEEE Eng Med Biol Soc 2023: 1-4 10.1109/embc40787.2023.10340930
Hindley N, Shieh CC, Keall P A patient-specific deep learning framework for 3D motion estimation and volumetric imaging during lung cancer radiotherapy Phys Med Biol 68(14) 10.1088/1361-6560/ace1d0
Lau BKF, Dillon O, Vinod SK, O’Brien RT, Reynolds T Faster and lower dose imaging: evaluating adaptive, constant gantry velocity and angular separation in fast low-dose 4D cone beam CT imaging Med Phys 10.1002/mp.16585
Liu PZY, Shan S, Waddington D, Whelan B, Dong B, Liney G, Keall P Rapid distortion correction enables accurate magnetic resonance imaging-guided real-time adaptive radiotherapy Phys Imaging Radiat Oncol 25: 100414 10.1016/j.phro.2023.100414
Lombardo E, Dhont J, Page D, Garibaldi C, Künzel LA, Hurkmans C, Tijssen RHN, Paganelli C, Liu PZY, Keall PJ, Riboldi M, Kurz C, Landry G, Cusumano D, Fusella M, Placidi L Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects Radiother Oncol 190: 109970 10.1016/j.radonc.2023.109970
Lombardo E, Liu PZY, Waddington DEJ, Grover J, Whelan B, Wong E, Reiner M, Corradini S, Belka C, Riboldi M, Kurz C, Landry G, Keall PJ Experimental comparison of linear regression and LSTM motion prediction models for MLC-tracking on an MRI-linac Med Phys 50(11): 7083-7092 10.1002/mp.16770
Reynolds T, Hatamikia S, Ma YQ, Dillon O, Gang G, Stayman JW, O’Brien R Technical note: Extended longitudinal and lateral 3D imaging with a continuous dual-isocenter CBCT scan Med Phys 50(4): 2372-2379 10.1002/mp.16234
Reynolds T, Ma Y, Wang T, Mei K, Noël PB, Gang GJ, Stayman JW Revealing pelvic structures in the presence of metal hip prothesis via non-circular CBCT orbits Proc SPIE Int Soc Opt Eng 12466 10.1117/12.2652980
Richardson M, Sidhom M, Keall P, Leigh L, Ball H, Bucci J, Gallagher S, Greer P, Hayden AJ, Kneebone A, Pryor D, Siva S, Martin J Genitourinary quality-of-life comparison between urethral sparing prostate stereotactic body radiation therapy monotherapy and virtual high-dose-rate brachytherapy boost Int J Radiat Oncol Biol Phys 116(5): 1069-1078 10.1016/j.ijrobp.2023.02.049
Sengupta C, Skouboe S, Ravkilde T, Poulsen PR, Nguyen DT, Greer PB, Moodie T, Hardcastle N, Hayden AJ, Turner S, Siva S, Tai KH, Martin J, Booth JT, O’Brien R, Keall PJ The dosimetric error due to uncorrected tumor rotation during real-time adaptive prostate stereotactic body radiation therapy Med Phys 50(1): 20-29 10.1002/mp.16094
Sengupta C, Nguyen DT, Moodie T, Mason D, Luo J, Causer T, Fan Liu S, Brown E, Inskip L, Hazem M, Chao M, Wang T, Lee YY, van Gysen K, Sullivan E, Cosgriff E, Ramachandran P, Poulsen P, Booth J, O’Brien R, Greer P, Keall P The first clinical implementation of real-time 6 degree-of-freedom Image-guided radiotherapy for liver SABR patients Radiother Oncol: 110031 10.1016/j.radonc.2023.110031
Shan S, Gao Y, Liu PZY, Whelan B, Sun H, Dong B, Liu F, Waddington DEJ Distortion-corrected image reconstruction with deep learning on an MRI-Linac Magn Reson Med 90(3): 963-977 10.1002/mrm.29684
Trada Y, Keall P, Jameson M, Moses D, Lin P, Chlap P, Holloway L, Min M, Forstner D, Fowler A, Lee MT Changes in serial multiparametric MRI and FDG-PET/CT functional imaging during radiation therapy can predict treatment response in patients with head and neck cancer Eur Radiol 33(12): 8788-8799 10.1007/s00330-023-09843-2
Trada Y, Lee MT, Jameson MG, Chlap P, Keall P, Moses D, Lin P, Fowler A Mid-treatment 18F-FDG PET imaging changes in parotid gland correlates to radiation-induced xerostomia Radiother Oncol 186: 109745 10.1016/j.radonc.2023.109745
Trada Y, Lin P, Lee MT, Jameson MG, Chlap P, Keall P, Moses D, Fowler A Impact of tumour region of interest delineation method for mid-treatment FDG-PET response prediction in head and neck squamous cell carcinoma undergoing radiotherapy Quant Imaging Med Surg 13(5): 2822-2836 10.21037/qims-22-798
Waddington DEJ, Hindley N, Koonjoo N, Chiu C, Reynolds T, Liu PZY, Zhu B, Bhutto D, Paganelli C, Keall PJ, Rosen MS Real-time radial reconstruction with domain transform manifold learning for MRI-guided radiotherapy Med Phys 50(4): 1962-1974 10.1002/mp.16224
Whelan B, Esnault L ParticlePhaseSpace: A python package for streamlined import, analysis, and export of particle phase space data J Open Source Software 8(89): 5375 10.21105/joss.05375
Whelan B, Loo BW, Jr., Wang J, Keall P TopasOpt: An open-source library for optimization with Topas Monte Carlo Med Phys 50(2): 1121-1131 10.1002/mp.16126
Yamamoto T, Kabus S, Bal M, Keall PJ, Moran A, Wright C, Benedict SH, Holland D, Mahaffey N, Qi L, Daly ME Four-dimensional computed tomography ventilation image-guided lung functional avoidance radiation therapy: A single-arm prospective pilot clinical trial Int J Radiat Oncol Biol Phys 115(5): 1144-1154 10.1016/j.ijrobp.2022.11.026

2022

AUTHORS TITLE PUBLICATION DOI
Ball HJ, Santanam L, Senan S, Tanyi JA, van Herk M and Keall PJ Results from the AAPM Task Group 324 respiratory motion management in radiation oncology survey. J Appl Clin Med Phys 23(11): e13810. 10.1002/acm2.13810
Begg J, Jelen U, Keall P, Liney G and Holloway L Experimental characterisation of the magnetic field correction factor, kB⃗, for Roos chambers in a parallel MRI-linac. Phys Med Biol 67(9). 10.1088/1361-6560/ac66b8
Brighi C, Keall PJ, Holloway LC, Walker A, Whelan B, de Witt Hamer PC, Verburg N, Aly F, Chen C, Koh ES and Waddington DEJ An investigation of the conformity, feasibility, and expected clinical benefits of multiparametric MRI-guided dose painting radiotherapy in glioblastoma. Neurooncol Adv 4(1): vdac134. 10.1093/noajnl/vdac134
Brighi C, Puttick S, Li S, Keall P, Neville K, Waddington D, Bourgeat P, Gillman A and Fay M A novel semiautomated method for background activity and biological tumour volume definition to improve standardisation of (18)F-FET PET imaging in glioblastoma. EJNMMI Phys 9(1): 9. 10.1186/s40658-022-00438-2
Brighi C, Salimova E, de Veer M, Puttick S and Egan G Reply to Letter from Price et al, re: Translation of focused ultrasound for blood-brain barrier opening in glioma. J Control Release. 10.1016/j.jconrel.2022.06.042
Brighi C, Salimova E, de Veer M, Puttick S and Egan G Translation of focused ultrasound for blood-brain barrier opening in glioma. J Control Release 345: 443-463. 10.1016/j.jconrel.2022.03.035
Brighi C, Verburg N, Koh ES, Walker A, Chen C, Pillay S, de Witt Hamer PC, Aly F, Holloway LC, Keall PJ and Waddington DEJ Repeatability of radiotherapy dose-painting prescriptions derived from a multiparametric magnetic resonance imaging model of glioblastoma infiltration. Phys Imaging Radiat Oncol 23: 8-15. 10.1016/j.phro.2022.06.004
Goodburn RJ, Philippens MEP, Lefebvre TL, Khalifa A, Bruijnen T, Freedman JN, Waddington DEJ, Younus E, Aliotta E, Meliadò G, Stanescu T, Bano W, Fatemi-Ardekani A, Wetscherek A, Oelfke U, van den Berg N, Mason RP, van Houdt PJ, Balter JM and Gurney-Champion OJ The future of MRI in radiation therapy: Challenges and opportunities for the MR community. Magn Reson Med 88(6): 2592-2608. 10.1002/mrm.29450
Grover J, Byrne HL, Sun Y, Kipritidis J and Keall P Investigating the use of machine learning to generate ventilation images from CT scans. Med Phys 48(8): 5258-5267. 10.1002/mp.15688
Hatamikia S, Biguri A, Herl G, Kronreif G, Reynolds T, Kettenbach J, Russ T, Tersol A, Maier A, Figl M, Siewerdsen JH and Birkfellner W Source-detector trajectory optimization in cone-beam computed tomography: a comprehensive review on today’s state-of-the-art. Phys Med Biol 67(16). 10.1088/1361-6560/ac8590
Hewson EA, Nguyen DT, Le A, Booth JT, Keall PJ and Mejnertsen L Optimising multi-target multileaf collimator tracking using real-time dose for locally advanced prostate cancer patients. Phys Med Biol 67(18). 10.1088/1361-6560/ac8967
Kanawati A, Constantinidis A, Williams Z, O’Brien R and Reynolds T Generating patient-matched 3D-printed pedicle screw and laminectomy drill guides from Cone Beam CT images: Studies in ovine and porcine cadavers. Med Phys 49(7): 4642-4652. 10.1002/mp.15681
Keall PJ, Brighi C, Glide-Hurst C, Liney G, Liu PZY, Lydiard S, Paganelli C, Pham T, Shan S, Tree AC, van der Heide UA, Waddington DEJ and Whelan B Integrated MRI-guided radiotherapy – opportunities and challenges. Nat Rev Clin Oncol. 19(7):458-470. 10.1038/s41571-022-00631-3
Keall PJ, Glide-Hurst CK, Cao M, Lee P, Murray B, Raaymakers BW, Tree A and van der Heide UA ICRU REPORT 97: MRI-Guided Radiation Therapy Using MRI-Linear Accelerators. Journal of the ICRU 22(1): 1-100. 10.1177/14736691221141950
Keall R, Keall P, Kiani C, Luckett T, McNeill R and Lovell M A systematic review of assessment approaches to predict opioid misuse in people with cancer. Support Care Cancer 30(7): 5645-5658. 10.1007/s00520-022-06895-w
Lau BKF, Reynolds T, Keall PJ, Sonke JJ, Vinod SK, Dillon O and O’Brien RT Reducing 4DCBCT imaging dose and time: exploring the limits of adaptive acquisition and motion compensated reconstruction. Phys Med Biol 67(6). 10.1088/1361-6560/ac55a4
Lydiard S, Pontré B, Lowe BS and Keall P Atrial fibrillation cardiac radioablation target visibility on magnetic resonance imaging. Phys Eng Sci Med 45(3): 757-767. 10.1007/s13246-022-01141-3
Ma Y, Gang GJ, Ehtiati T, Reynolds T, Russ T, Wang W, Weiss C, Theodore N, Hong K, Siewerdsen J and Stayman JW Non-circular CBCT orbit design and realization on a clinical robotic C-arm for metal artifact reduction. Proc SPIE Int Soc Opt Eng 12034. 10.1117/12.2612448
Martin P, Holloway L, Metcalfe P, Koh ES and Brighi C Challenges in Glioblastoma Radiomics and the Path to Clinical Implementation. Cancers (Basel) 14(16). 10.3390/cancers14163897
Montinola D, McNamara AL, Kuncic Z and Byrne HL Investigation of Micron-Scale Radiotherapy Dose Deposition in the Lung: Effect of Magnetic Field and Nanoparticles—a Monte Carlo Simulation. Frontiers in Physics 10. 10.3389/fphy.2022.835016
Morton N, Keall P, O’Brien R and Reynolds T CArdiac and REspiratory adaptive Computed Tomography (CARE-CT): a proof-of-concept digital phantom study. Phys Eng Sci Med 45(4): 1257-1271. 10.1007/s13246-022-01193-5
Morton N, O’Brien R, Keall P and Reynolds T System requirements to improve adaptive 4-dimensional computed tomography (4D CT) imaging. Biomed Phys Eng Express 8(6). 10.1088/2057-1976/ac9849
Mueller M, Booth J, Briggs A, Jayamanne D, Panettieri V, Senthi S, Shieh CC and Keall P MArkerless image Guidance using Intrafraction Kilovoltage x-ray imaging (MAGIK): study protocol for a phase I interventional study for lung cancer radiotherapy. BMJ Open 12(1): e057135. 10.1136/bmjopen-2021-057135
Mueller M, Poulsen P, Hansen R, Verbakel W, Berbeco R, Ferguson D, Mori S, Ren L, Roeske JC, Wang L, Zhang P and Keall P The markerless lung target tracking AAPM Grand Challenge (MATCH) results. Med Phys 49(2): 1161-1180. 10.1002/mp.15418
Pham TT, Whelan B, Oborn BM, Delaney GP, Vinod S, Brighi C, Barton M and Keall P Magnetic resonance imaging (MRI) guided proton therapy: A review of the clinical challenges, potential benefits and pathway to implementation. Radiother Oncol 170: 37-47. 10.1016/j.radonc.2022.02.031
Reynolds T, Ma YQ, Kanawati AJ, Constantinidis A, Williams Z, Gang G, Dillon O, Russ T, Wang W, Ehtiati T, Weiss CR, Theodore N, Siewerdsen JH, Stayman JW and O’Brien RT Extended Intraoperative Longitudinal 3-Dimensional Cone Beam Computed Tomography Imaging With a Continuous Multi-Turn Reverse Helical Scan. Invest Radiol 57(11): 764-772. 10.1097/rli.0000000000000885
Russ T, Ma YQ, Golla AK, Bauer DF, Reynolds T, Tönnes C, Hatamikia S, Schad LR, Zöllner FG, Gang GJ, Wang W and Stayman JW Fast CBCT Reconstruction using Convolutional Neural Networks for Arbitrary Robotic C-arm Orbits. Proc SPIE Int Soc Opt Eng 12031. 10.1117/12.2612935
Sengupta C, Skouboe S, Ravkilde T, Poulsen PR, Nguyen DT, Greer PB, Moodie T, Hardcastle N, Hayden AJ, Turner S, Siva S, Tai KH, Martin J, Booth JT, O’Brien R and Keall PJ The dosimetric error due to uncorrected tumor rotation during real-time adaptive prostate stereotactic body radiation therapy. Med Phys. 10.1002/mp.16094
Smith L, Byrne HL, Waddington D and Kuncic Z Nanoparticles for MRI-guided radiation therapy: a review. Cancer Nanotechnology 13(1): 38. 10.1186/s12645-022-00145-8
Whelan B, Loo BW, Jr., Wang J and Keall P TopasOpt: An open-source library for optimization with Topas Monte Carlo. Med Phys. 10.1002/mp.16126
Whelan B, Trovati S, Wang J, Fahrig R, Maxim PG, Hanuka A, Shumail M, Tantawi S, Merrick J, Perl J, Keall P and Jr BWL Bayesian optimization to design a novel x-ray shaping device. Med Phys. 10.1002/mp.15887
Yamamoto T, Kabus S, Bal M, Keall PJ, Moran A, Wright C, Benedict SH, Holland D, Mahaffey N, Qi L and Daly ME Four-Dimensional Computed Tomography Ventilation Image Guided Lung Functional Avoidance Radiation Therapy: A Single-Arm Prospective Pilot Clinical Trial. Int J Radiat Oncol Biol Phys. 10.1016/j.ijrobp.2022.11.026

2021

AUTHOR TITLE PUBLICATION DOI
Booth J, Caillet V, Briggs A, Hardcastle N, et al. MLC tracking for lung SABR is feasible, efficient and delivers high-precision target dose and lower normal tissue dose Radiotherapy and Oncology. 2021;155:131-137 10.1016/j.radonc.2020.10.036
Buckley JG, Dowling JA, Sidhom M, Liney GP, et al. Pelvic organ motion and dosimetric implications during horizontal patient rotation for prostate radiation therapy Medical Physics. 2021;48(1):397-413 10.1002/mp.14579
Buckley JG, Smith AB, Sidhom M, Rai R, et al. Measurements of human tolerance to horizontal rotation within an MRI scanner: Towards gantry-free radiation therapy Journal of Medical Imaging and Radiation Oncology. 2021;65(1):112-119 10.1111/1754-9485.13130
Gardner M, Dillon O, Shieh CC, O’Brien R, et al. The adaptation and investigation of cone-beam CT reconstruction algorithms for horizontal rotation fixed-gantry scans of rabbits Physics in Medicine and Biology. 2021;66(10):105012 10.1088/1361-6560/abf9dd
Hardcastle N, Briggs A, Caillet V, Angelis G, et al. Quantification of the geometric uncertainty when using implanted markers as a surrogate for lung tumor motion Medical Physics. 2021;48(6):2724-2732 10.1002/mp.14788
Hewson EA, Dipuglia A, Kipritidis J, Ge Y, et al. First experimental evaluation of multi-target multileaf collimator tracking during volumetric modulated arc therapy for locally advanced prostate cancer Radiotherapy and Oncology. 2021;160:29-34 10.1016/j.radonc.2021.05.001
Hewson EA, Ge Y, O’Brien R, Roderick S, et al. Adapting to the motion of multiple independent targets using multileaf collimator tracking for locally advanced prostate cancer: Proof of principle simulation study Medical Physics. 2021;48(1):114-124 10.1002/mp.14572
Hindley N, Lydiard S, Shieh CC, Keall P. Proof-of-concept for x-ray based real-time image guidance during cardiac radioablation Physics in Medicine and Biology. 2021;66(17) 10.1088/1361-6560/ac1834
Keall PJ, Sawant A, Berbeco RI, Booth JT, et al. AAPM Task Group 264: The safe clinical implementation of MLC tracking in radiotherapy Medical Physics. 2021;48(5):e44-e64 10.1002/mp.14625
Lau BKF, Reynolds T, Wallis A, Smith S, et al. Reducing 4DCBCT scan time and dose through motion compensated acquisition and reconstruction Physics in Medicine and Biology. 2021;66(7):075002 10.1088/1361-6560/abebfb
Lee YYD, Nguyen DT, Moodie T, O’Brien R, et al. Study protocol of the LARK (TROG 17.03) clinical trial: a phase II trial investigating the dosimetric impact of Liver Ablative Radiotherapy using Kilovoltage intrafraction monitoring BMC Cancer. 2021;21(1):494 10.1186/s12885-021-08184-x
Liu PZY, Gardner M, Heng SM, Shieh CC, et al. Pre-treatment and real-time image guidance for a fixed-beam radiotherapy system Physics in Medicine and Biology. 2021;66(6):064003 10.1088/1361-6560/abdc12
Lydiard S, Blanck O, Hugo G, O’Brien R, Keall P. A Review of Cardiac Radioablation (CR) for Arrhythmias: Procedures, Technology, and Future Opportunities International Journal of Radiation Oncology Biology Physics. 2021;109(3):783-800 10.1016/j.ijrobp.2020.10.036
Lydiard S, Pontré B, Hindley N, Lowe BS, et al. MRI-guided cardiac-induced target motion tracking for atrial fibrillation cardiac radioablation Radiotherapy and Oncology. 2021;164:138-145 10.1016/j.radonc.2021.09.025
Lydiard S, Pontré B, Lowe BS, Ball H, et al. Cardiac radioablation for atrial fibrillation: Target motion characterization and treatment delivery considerations Medical Physics. 2021;48(3):931-941 10.1002/mp.14661
Mejnertsen L, Hewson E, Nguyen DT, Booth J, Keall P. Dose-based optimisation for multi-leaf collimator tracking during radiation therapy Physics in Medicine and Biology. 2021;66(6):065027 10.1088/1361-6560/abe836
Mueller M, Booth J, Briggs A, Jayamanne D, et al. The markerless lung target tracking AAPM Grand Challenge (MATCH) results Medical Physics. 2021 10.1002/mp.15418
Muurholm CG, Ravkilde T, Skouboe S, Worm E, et al. Real-time dose-guidance in radiotherapy: Proof of principle Radiotherapy and Oncology. 2021;164:175-182 10.1016/j.radonc.2021.09.024
Mylonas A, Booth J, Nguyen DT. A review of artificial intelligence applications for motion tracking in radiotherapy Journal of Medical Imaging and Radiation Oncology. 2021;65(5):596-611 10.1111/1754-9485.13285
Nguyen DT, Keall P, Booth J, Shieh CC, et al. A real-time IGRT method using a Kalman filter framework to extract 3D positions from 2D projections Physics in Medicine and Biology. 2021;66(21) 10.1088/1361-6560/ac06e3
O’Brien RT, Dillon O, Lau B, George A, et al. The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy Radiotherapy and Oncology. 2021;161:29-34 10.1016/j.radonc.2021.05.021
Reynolds T, Dillon O, Prinable J, Whelan B, et al. Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT): Developing the next generation of cardiac cone beam CT imaging Medical Physics. 2021;48(5):2543-2552 10.1002/mp.14811
Reynolds T, Lim P, Keall PJ, O’Brien R. Minimizing 4DCBCT imaging dose and scan time with Respiratory Motion Guided 4DCBCT: A pre-clinical investigation Biomedical Physics and Engineering Express. 2021;7(2) 10.1088/2057-1976/abdc82
Zwan BJ, Caillet V, Booth JT, Colvill E, et al. Toward real-time verification for MLC tracking treatments using time-resolved EPID imaging Medical Physics. 2021;48(3):953-964 10.1002/mp.14675

2020

AUTHOR TITLE PUBLICATION DOI
Boele, T., Waddington, D. E. J., Gaebel, T., Rej, E., Hasija, A., Brown, L. J., McCamey, D. R., Reilly, D. J. Tailored nanodiamonds for hyperpolarized C 13 MRI Physical Review B, Volume 101, Issue 15 10.1103/PhysRevB.101.155416
Buckley, J. G., Dowling, J. A., Sidhom, M., Liney, G. P., Rai, R., Metcalfe, P. E., Holloway, L. C., Keall, P. J. Pelvic organ motion and dosimetric implications during horizontal patient rotation for prostate radiation therapy Medical Physics 10.1002/mp.14579
Buckley, J. G., Smith, A. B., Sidhom, M., Rai, R., Liney, G. P., Dowling, J. A., Metcalfe, P. E., Holloway, L. C., Keall, P. J. Measurements of human tolerance to horizontal rotation within an MRI scanner: Towards gantry-free radiation therapy Journal of Medical Imaging and Radiation Oncology 10.1111/1754-9485.13130
Booth J., Caillet V., Briggs A., et al. MLC tracking for lung SABR is feasible, efficient and delivers high-precision target dose and lower normal tissue dose Radiotherapy and Oncology, Volume 155, February 2021, Pages 131-137 10.1016/j.radonc.2020.10.036
Caillet V., Zwan B., Briggs A., et al. Geometric uncertainty analysis of MLC tracking for lung SABR Physics in Medicine and Biology 10.1088/1361-6560/abb0c6
De Deene, Y., Wheatley, M., Dong, B., Roberts, N., Jelen, U., Waddington, D., Liney, G. Towards real-time 4D radiation dosimetry on an MRI-Linac Physics in Medicine and Biology, Volume 65, Issue 22 10.1088/1361-6560/abb9f7
Dillon O., Keall P. J., Shieh C.-C., O’Brien R. T. Evaluating Reconstruction Algorithms for Respiratory Motion Guided Acquisition Physics in Medicine and Biology, Volume 65, Number 17 10.1088/1361-6560/ab98d3
Dunbar M., O’Brien R., Froyland G. Optimising lung imaging for cancer radiation therapy European Journal of Operational Research, 282(3), 1038-1052 10.1016/j.ejor.2019.10.020
Hewson E. A., Ge Y., O’Brien R., Roderick S., Bell L., Poulsen P. R., et al. Adapting to the motion of multiple independent targets using multileaf collimator tracking for locally advanced prostate cancer: Proof of principle simulation study Medical Physics 10.1002/mp.14572
Hewson E. A., Nguyen D. T., O’Brien R., Poulsen P. R., Booth J. T., et al. Is multileaf collimator tracking or gating a better intrafraction motion adaptation strategy? An analysis of the TROG 15.01 SPARK trial Radiotherapy and Oncology, Volume 151, Pages 234-241 10.1016/j.radonc.2020.08.010
Jelen U., Dong B., Begg J., Roberts N., Whelan B., Keall P., Liney G. Dosimetric Optimization and Commissioning of a High Field Inline MRI-Linac Frontiers in Oncology, 10 10.3389/fonc.2020.00136
Keall P., Nguyen D., O’Brien R., et al. Real-Time Image Guided Ablative Prostate Cancer Radiation Therapy Results from the TROG 15.01 SPARK Trial International Journal of Radiation Oncology Biology Physics, Volume 107, Issue 3 10.1016/j.ijrobp.2020.03.014
Keall P. J., Sawant A., Berbeco R. I., et al. AAPM Task Group 264 on The Safe Clinical Implementation of MLC Tracking in Radiotherapy Medical Physics 10.1002/mp.14625
Kueng R., Oborn B.M., Roberts N.F., Causer T., Stampanoni M.F.M., Mansera P., Keall P.J., Fix M.K. Towards MR-guided electron therapy: measurement and simulation of clinical electron beams in magnetic fields Physica Medica, Volume 78, October 2020, Pages 83-92 10.1016/j.ejmp.2020.09.001
Kurz C., Buizza G., Landry G., Kamp F., Rabe M., Paganelli C., et al. Medical physics challenges in clinical MR-guided radiotherapy Radiation Oncology, 15(1) 10.1186/s13014-020-01524-4
Liu, P. Z. Y., Dong, B., Nguyen, D. T., Ge, Y., Hewson, E. A., et al. First experimental investigation of simultaneously tracking two independently moving targets on an MRI-linac using real-time MRI and MLC tracking Medical Physics, Volume 47, Issue 12, pgs 6440-6449 10.1002/mp.14536
Lydiard S., Hugo, G., O’Brien, R., Blanck, O., Keall P. A review of cardiac radioablation (CR) for arrhythmias: procedures, technology and future opportunities Int J Radiat Oncol Biol Phys 10.1002/mp.14661
Lydiard S., Pontré B., Lowe B. S., Ball H., Sasso G., Keall P. Cardiac radioablation for atrial fibrillation: target motion characterization and treatment delivery considerations Medical Physics 10.1002/mp.14661
Morton N., Sykes J., Barber J., Hofmann C., Keall P., O’Brien R. Reducing 4D CT imaging artifacts at the source: First experimental results from the respiratory adaptive computed tomography (REACT) system Physics in Medicine and Biology, 65(7) 10.1088/1361-6560/ab7abe
Mueller M., Zolfaghari R., Briggs A., Furtado H., Booth J., et al. The first prospective implementation of markerless lung target tracking in an experimental quality assurance procedure on a standard linear accelerator Physics in Medicine and Biology, 65(2), 1-13 10.1088/1361-6560/ab5d8b
Poulsen P., Murtaza G., Worm E., Ravkilde T., O’Brien R., et al. Simulated multileaf collimator tracking for stereotactic liver radiotherapy guided by kilovoltage intrafraction monitoring Radiotherapy and Oncology, 144, 93-100 10.1016/j.radonc.2019.11.008
Scarpelli M., Whelan B., Farahaniain K. Domain Classification and Analysis of National Institutes of Health Funded Medical Physics Research Medical Physics 10.1002/mp.14469
Reynolds T., Dillon O., Prinable J., Whelan B., Keall P. J., O’Brien R. T. Toward improved 3D carotid artery imaging with Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT) Medical Physics 10.1002/mp.14462
Shi K., Dipuglia A., Booth J., Alnaghy S., Kyme A., Keall P., Nguyen D. T. Experimental evaluation of the dosimetric impact of intrafraction prostate rotation using film measurement with a 6DoF robotic arm Medical Physics, Volume 47, Issue 12, Pages 6068-6076 10.1002/mp.14502
Waddington D. E. J., Boele T., Maschmeyer R., Kuncic Z., Rosen M. S. High-sensitivity in vivo contrast for ultra-low field magnetic resonance imaging using superparamagnetic iron oxide nanoparticles Science Advances, Volume 6, Number 29 10.1126/sciadv.abb0998
Whelan B., Leghissa M., Amrein P., Zaitsev M., Heinrich B., Fahrig R., Rohdjess H. Magnetic modelling of actively shielded rotating MRI magnets in the presence of environmental steel Physics in Medicine and Biology 10.1088/1361-6560/abd010
Zwan B. J., Caillet V., Booth J. T., Colvill E., Fuangrod T., et al. Toward real‐time verification for MLC tracking treatments using time resolved EPID imaging Medical Physics 10.1002/mp.14675

2019

Alnaghy S, Kyme A, Caillet V, et al. A six-degree-of-freedom robotic motion system for quality assurance of real-time image-guided radiotherapy. Physics in Medicine and Biology. 2019;64(10).

Bertholet J, Knopf AC, Eiben B, et al. Real-time intrafraction motion monitoring in external beam radiotherapy. Physics in Medicine and Biology. 2019; doi: 10.1088/1361-6560/ab2ba8.

Caillet V, O’Brien R, Moore D, et al. Technical Note: In silico and experimental evaluation of two leaf-fitting algorithms for MLC tracking based on exposure error and plan complexity. Medical Physics. 2019;46(4):1814-1820.

Cooper BJ, O’Brien RT, Shieh CC, Keall PJ. Real-time respiratory triggered four dimensional cone-beam CT halves imaging dose compared to conventional 4D CBCT. Physics in Medicine and Biology. 2019;64(7).

Garau N, Via R, Meschini G, et al. A ROI-based global motion model established on 4DCT and 2D cine-MRI data for MRI-guidance in radiation therapy. Physics in Medicine and Biology. 2019;64(4).

Hegi-Johnson F, de Ruysscher D, Keall P, et al. Imaging of regional ventilation: Is CT ventilation imaging the answer? A systematic review of the validation data. Radiotherapy and Oncology. 2019;137:175-185.

Hindley N, Booth J, Keall P, Shieh CC. Real-time direct diaphragm tracking using kV imaging on a standard linear accelerator. Medical Physics. 2019; Accepted for publication.

Keall P, Kron T, Zaidi H. In the future, emission-guided radiation therapy will play a critical role in clinical radiation oncology. Medical Physics. 2019;46(4):1519-1522.

Keall P, Poulsen P, Booth JT. See, Think, and Act: Real-Time Adaptive Radiotherapy. Seminars in Radiation Oncology. 2019;29(3):228-235.

Keall PJ, Nguyen DT, O’Brien R, Zhang P, Bertholet J, Poulsen PR. In Reply to Dahele and Verbakel. International Journal of Radiation Oncology Biology Physics. 2019;103(1):283-284.

Kipritidis J, Tahir BA, Cazoulat G, et al. The VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging. Medical Physics. 2019;46(3):1198-1217.

Lee D, Kim S, Palta J, Lewis B, Keall P, Kim T. A retrospective 4D-MRI based on 2D diaphragm profiles for lung cancer patients. Journal of Medical Imaging and Radiation Oncology. 2019;63(3):360-369.

Liney GP, Jelen U, Byrne H, et al. Technical Note: The first live treatment on a 1.0 Tesla inline MRI-linac. Medical Physics. 2019;46(7):3254-3258.

Liu PZY, O’Brien R, Heng SM, et al. Development and commissioning of a full-size prototype fixed-beam radiotherapy system with horizontal patient rotation. Medical Physics. 2019;46(3):1331-1340.

Maxim PG, Keall P, Cai J. FLASH Radiotherapy: Newsflash or Flash in The Pan? Medical Physics. 2019; doi: 10.1002/mp.13685.

Mylonas A, Keall PJ, Booth JT, et al. A deep learning framework for automatic detection of arbitrarily shaped fiducial markers in intrafraction fluoroscopic images. Medical Physics. 2019;46(5):2286-2297.

Pinkham DW, Negahdar M, Yamamoto T, et al. A Feasibility Study of Single-inhalation, Single-energy Xenon-enhanced CT for High-resolution Imaging of Regional Lung Ventilation in Humans. Academic Radiology. 2019;26(1):38-49.

Reynolds T, Shieh CC, Keall PJ, O’Brien RT. Towards patient connected imaging with ACROBEAT: Adaptive CaRdiac cOne BEAm computed Tomography. Physics in Medicine and Biology. 2019;64(6).

Reynolds T, Shieh CC, Keall PJ, O’Brien RT. Dual cardiac and respiratory gated thoracic imaging via adaptive gantry velocity and projection rate modulation on a linear accelerator: A Proof-of-Concept Simulation Study. Physics in Medicine and Biology. 2019; doi: 10.1002/mp.13670.

Shieh CC, Gonzalez Y, Li B, et al. SPARE: Sparse-view reconstruction challenge for 4D cone-beam CT from a 1-min scan. Medical Physics. 2019; doi: 10.1002/mp.13687.

Steiner E, Shieh CC, Caillet V, et al. Both four-dimensional computed tomography and four-dimensional cone beam computed tomography under-predict lung target motion during radiotherapy. Radiotherapy and Oncology. 2019;135:65-73.

Wolf J, Nicholls J, Hunter P, Nguyen DT, Keall P, Martin J. Dosimetric impact of intrafraction rotations in stereotactic prostate radiotherapy: A subset analysis of the TROG 15.01 SPARK trial. Radiotherapy and Oncology. 2019;136:143-147.

2018

Liu PZY, O’Brien R, Heng SM, Newall M, Downes S, Shieh CC, Corde S, Jackson M, Keall P. Development and commissioning of a full-size prototype fixed-beam radiotherapy system with horizontal patient rotation. Med Phys. 2018 Dec 24. doi: 10.1002/mp.13356. [Epub ahead of print] [More Information]

Kipritidis J, Tahir BA, Cazoulat G, Hofman MS, Siva S, Callahan J, Hardcastle N, Yamamoto T, Christensen GE, Reinhardt JM, Kadoya N, Patton TJ, Gerard SE, Duarte I, Archibald-Heeren B, Byrne M, Sims R, Ramsay S, Booth JT, Eslick E, Hegi-Johnson F, Woodruff HC, Ireland RH, Wild JM, Cai J, Bayouth JE, Brock K, Keall PJ. The VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging. Med Phys. 2018 Dec 21. doi: 10.1002/mp.13346. [More Information]

Steiner E, Shieh CC, Caillet V, Booth J, Hardcastle N, Briggs A, Jayamanne D, Haddad C, Eade T, Keall P. 4-Dimensional Cone Beam Computed Tomography-Measured Target Motion Underrepresents Actual Motion. Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):932-940. doi: 10.1016/j.ijrobp.2018.04.056. Epub 2018 Apr 27. [More Information]

Paganelli C, Whelan B, Peroni M, Summers P, Fast M, van de Lindt T, McClelland J, Eiben B, Keall P, Lomax T, Riboldi M, Baroni G. MRI-guidance for motion management in external beam radiotherapy: current status and future challenges. Phys Med Biol. 2018 Nov 20;63(22):22TR03. doi: 10.1088/1361-6560/aaebcf. [More Information]

Lydiard S, Caillet V, Ipsen S, O’Brien R, Blanck O, Poulsen PR, Booth J, KeallP. Investigating multi-leaf collimator tracking in stereotactic arrhythmic radioablation (STAR) treatments for atrial fibrillation. Phys Med Biol. 2018 Sep 28;63(19):195008. doi: 10.1088/1361-6560/aadf7c [More Information]

Liney GP, Whelan B, Oborn B, Barton M, Keall P. MRI-Linear Accelerator Radiotherapy Systems. Clin Oncol (R Coll Radiol). 2018 Nov;30(11):686-691. doi: 10.1016/j.clon.2018.08.003. [More Information]

Shieh CC, Barber J, Counter W, Sykes JR, Bennett P, Heng SM, White P, Corde S, Jackson M, Ahern V, Feain IJ, O’Brien RT, Keall PJ. Cone-beam CT reconstruction with gravity-induced motion. Phys Med Biol. 2018 Sep 17. doi: 10.1088/1361-6560/aae1bb. [More Information]

Lydiard S, Caillet V, Ipsen S, O’Brien R, Blanck O, Poulsen PR, Booth J, Keall P. Investigating multi-leaf collimator tracking in stereotactic arrhythmic radioablation (STAR) treatments for atrial fibrillation. Phys Med Biol. 2018 Sep 28;63(19). doi: 10.1088/1361-6560/aadf7c. PubMed PMID: 30189419. [More Information]

Nguyen DT, Booth JT, Caillet V, Hardcastle N, Briggs A, Haddad C, Eade T, O’Brien R, Keall PJ. An augmented correlation framework for the estimation of tumour translational and rotational motion during external beam radiotherapy treatments using intermittent monoscopic x-ray imaging and an external respiratory signal. Phys Med Biol. 2018 Oct 9;63(20). doi: 10.1088/1361-6560/aadf2c. [More Information]

P. Z. Y. Liu D. T. Nguyen I. Feain R. O’Brien P. Keall J. T Booth Technical note: Real-time image-guided adaptive radiotherapy of a rigid target for a prototype fixed beam radiotherapy system.Med Phys. 2018 Aug;45(8). doi: 10.1002/mp.13143. Epub 2018 Aug 22. [More Information]

Martin S, O’ Brien R, Hofmann C, Keall P, Kipriditis J. An in silico performance characterization of respiratory motion guided 4DCT for high-quality low-dose lung cancer imaging.Phys Med Biol. 2018 Jul 27;63(15):155012. doi: 10.1088/1361-6560/aaceca. [More Information]

Muller M, Paganelli C, Keall P. A phantom study to create synthetic CT from orthogonal two dimensional cine MRI and evaluate the effect of irregular breathing. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:4162-4165. doi: 10.1109/EMBC.2018.8513236. [More Information]

Paganelli C, Kipritidis J, Lee D, Baroni G, Keall P, Riboldi M. Image-based retrospective 4D MRI in external beam radiotherapy: A comparative study with a digital phantom. Phys Med Biol. 2018 Jul 27;63(15):155012. doi: 10.1088/1361-6560/aaceca [More Information]

Liney GP, Dong B, Weber E, Rai R, Destruel A, Garcia-Alvarez R, Manton DJ, Jelen U, Zhang K, Barton M, Keall P, Crozier S. Imaging performance of a dedicated radiation transparent RF coil on a 1.0 Tesla inline MRI-linac. Phys Med Biol. 2018 Jun 25;63(13):135005. doi: 10.1088/1361-6560/aac813.[More Information]

Paganelli C, Lee D, Kipritidis J, Whelan B, Greer PB, Baroni G, Riboldi M,
Keall P. Feasibility study on 3D image reconstruction from 2D orthogonal cine-MRI for MRI-guided radiotherapy. J Med Imaging Radiat Oncol. 2018 Jun;62(3):389-400. doi:10.1111/1754-9485.12713. [More Information]

Keall PJ, Colvill E, O’Brien R, Caillet V, Eade T, Kneebone A, Hruby G,
Poulsen PR, Zwan B, Greer PB, Booth J. Electromagnetic-Guided MLC Tracking Radiation Therapy for Prostate Cancer Patients: Prospective Clinical Trial Results. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):387-395. doi:10.1016/j.ijrobp.2018.01.098.
[More Information]

Martin JM, Supiot S, Keall PJ, Catton CN. Moderately hypofractionated prostate external-beam radiotherapy: an emerging standard. Br J Radiol. 2018 Jun;91(1086):20170807. doi:10.1259/bjr.20170807. [More Information]

Duncan M, Newall MK, Caillet V, Booth JT, Keall PJ, Lerch M, Perevertaylo V, Rosenfeld AB, Petasecca M. Real-time high spatial resolution dose verification in stereotactic motion adaptive arc radiotherapy. J Appl Clin Med Phys. 2018 Jun 5. doi:10.1002/acm2.12364. [More Information]

Yamamoto T, Kabus S, Bal M, Bzdusek K, Keall PJ, Wright C, Benedict SH, Daly ME. Changes in Regional Ventilation During Treatment and Dosimetric Advantages of CT Ventilation Image Guided Radiation Therapy for Locally Advanced Lung Cancer. Int J Radiat Oncol Biol Phys. 2018 May 4. pii: S0360-3016(18)30741-7. doi:10.1016/j.ijrobp.2018.04.063. [More Information]

Liney GP, Dong B, Weber E, Rai R, Destruel A, Garcia-Alvarez R, Manton D, Jelen U, Zhang K, Barton M, Keall PJ, Crozier S. Imaging performance of a dedicated radiation transparent RF coil on a 1.0 Tesla inline MRI-linac. Phys Med Biol. 2018 May 25. doi:10.1088/1361-6560/aac813. [More Information]

Toftegaard J, Keall PJ, O’Brien R, Ruan D, Ernst F, Homma N, Ichiji K,
Poulsen PR. Potential improvements of lung and prostate MLC tracking investigated by treatment simulations. Med Phys. 2018 May;45(5):2218-2229. doi:10.1002/mp.12868. [More Information]

Paganelli C, Kipritidis J, Lee D, Baroni G, Keall P, Riboldi M. Image-based retrospective 4D MRI in external beam radiotherapy: A comparative study with a digital phantom. Med Phys. 2018 May 14. doi:10.1002/mp.12965. [More Information]

Whelan, B. An update of NIH research funding of AAPM members from 1985 to 2017 Medical Physics. (23/5/2018) [More Information]

Barber, J.,Shieh, CC.,Counter, W.,Sykes ,JR.,Bennett, P., Ahern, V.,Corde, S.,Heng, SM.,White, P.,Jackson, M.,Liu, P.,Keall, PJ.,Feain, I. A CBCT study of the gravity-induced movement in rotating rabbits. Physics in Medicine & Biology. (2018) [More Information]

Keall PJ, Nguyen DT, O’Brien R, Caillet V, Hewson E, Poulsen PR, Bromley R, Bell L, Eade T, Kneebone A, Martin J, Booth JT. The first clinical implementation of real-time image-guided adaptive radiotherapy using a standard linear accelerator. Radiother Oncol. 2018 Apr;127(1):6-11. doi:10.1016/j.radonc.2018.01.001. [More Information]

Keall PJ, Nguyen DT, O’Brien R, Zhang P, Happersett L, Bertholet J, Poulsen PR. Review of Real-Time 3-Dimensional Image Guided Radiation Therapy on Standard-Equipped Cancer Radiation Therapy Systems: Are We at the Tipping Point for the Era of Real-Time Radiation Therapy? Int J Radiat Oncol Biol Phys. 2018 Apr 14. pii: S0360-3016(18)30668-0. [More Information]

Chapman CH, McGuinness C, Gottschalk AR, Yom SS, Garsa AA, Anwar M, Braunstein SE, Sudhyadhom A, Keall P, Descovich M. Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy. J Appl Clin Med Phys. 2018 Apr 26. doi:10.1002/acm2.12338. [More Information]

Pinkham DW, Negahdar M, Yamamoto T, Mittra E, Diehn M, Nair VS, Keall PJ, Maxim PG, Loo BW Jr. A Feasibility Study of Single-inhalation, Single-energy Xenon-enhanced CT for High-resolution Imaging of Regional Lung Ventilation in Humans. Acad Radiol. 2018 Mar 29. pii: S1076-6332(18)30119-3. [More Information]

Kim, JH., T. Nguyen, DT, Booth, J., Huang, C., Fuangrod, T, Poulsen, P., O’Brien, R., Caillet, V., Eade, T., Kneebone, A., Keall, P. (2018). The accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom prostate motion measurements during patient treatments. Radiotherapy and Oncology. 126(2). (236-243) [More Information]

Lee, D., Greer, P., Paganelli, C. Ludbrook, JJ., Kim, T., Keall,P. (2018). Audiovisual biofeedback improves the correlation between internal/external surrogate motion and lung tumor motion. MedPhys, 45(3), 1009-1017. [More Information]

Whelan, B., Kolling, S., Oborn, B., Keall, P. (2018) Passive magnetic shielding in MRI-Linac systems. Physics in Medicine & Biology, 63(7), 075-008. [More Information]

Montanaro T, Nguyen DT, Keall PJ, Booth J, Caillet V, Eade T, Haddad C, Shieh CC. A comparison of gantry-mounted x-ray-based real-time target tracking methods. Med Phys. 2018 Mar;45(3):1222-1232. [More Information]

Pollock S, Tse R, Martin D, McLean L, Pham M, Tait D, Estoesta R, Whittington G, Turley J, Kearney C, Cho G, Hill R, Pickard S, Aston P, Makhija K, O’Brien R, Keall P. Impact of audiovisual biofeedback on interfraction respiratory motion reproducibility in liver cancer stereotactic body radiotherapy. J Med Imaging Radiat Oncol. 2018 Feb;62(1):133-139. [More Information]

Lowther N, Ipsen S, Marsh S, Blanck O, Keall P. Investigation of the XCAT phantom as a validation tool in cardiac MRI tracking algorithms. Phys Med. 2018
Jan;45:44-51. [More Information]

2017

  • Zwan BJ, Barnes MP, Hindmarsh J, Lim SB, Lovelock DM, Fuangrod T, O’Connor DJ, Keall PJ, Greer PB. Commissioning and quality assurance for VMAT delivery systems: An efficient time-resolved system using real-time EPID imaging.Australas Phys Eng Sci Med. 2017 Sep;40(3):643-649. doi: 10.1007/s13246-017-0572-0[More Information]
  • Oborn BM, Dowdell S, Metcalfe PE, Crozier S, Mohan R, Keall PJ. Future of medical physics: Real-time MRI-guided proton therapy.Med Phys. 2017 Aug;44(8):e77-e90. doi: 10.1002/mp.12371[More Information]
  • Hegi-Johnson F, Keall P, Barber J, Bui C, Kipritidis J. Evaluating the accuracy of 4D-CT ventilation imaging: First comparison with Technegas SPECT ventilation.Med Phys. 2017 Aug;44(8):4045-4055. doi: 10.1002/mp.12317[More Information]
  • Feain I, Coleman L, Wallis H, Sokolov R, O’Brien R, Keall P. Technical Note: The design and function of a horizontal patient rotation system for the purposes of fixed-beam cancer radiotherapy.Med Phys. 2017 Jun;44(6):2490-2502. doi: 10.1002/mp.12219.[More Information]
  • Shieh, C., Caillet, V., Dunbar, M., Keall, P., Booth, J., Hardcastle, N., Haddad, C., Eade, T., Feain, I. (2017). A Bayesian approach for three-dimensional markerless tumor tracking using kV imaging during lung radiotherapy. Physics in Medicine and Biology, 62(8), 3065-3080. [More Information]
  • Hugo, G., Weiss, E., Sleeman, W., Balik, S., Keall, P., Lu, J., Williamson, J. (2017). A longitudinal four-dimensional computed tomography and cone beam computed tomography dataset for image-guided radiation therapy research in lung cancer. Medical Physics, 44(2), 762-771. [More Information]
  • Whelan, B., Liney, G., Dowling, J., Rai, R., Holloway, L., McGarvie, L., Feain, I., Barton, M., Berry, M., Wilkins, R., Keall, P. (2017). An MRI-compatible patient rotation system – design, construction, and first organ deformation results. Medical Physics, 44(2), 581-588. [More Information]
  • Lee, D., Greer, P., Lapuz, C., Ludbrook, J., Hunter, P., Arm, J., Pollock, S., Makhija, K., O’Brien, R., Kim, T., Keall, P. (2017). Audiovisual biofeedback guided breath-hold improves lung tumor position reproducibility and volume consistency. Advances in Radiation Oncology, In Press, 1-9.
  • Whelan, B., Moros, E., Fahrig, R., Deye, J., Yi, T., Woodward, M., Keall, P., Siewerdsen, J. (2017). Development and testing of a database of NIH research funding of AAPM members: A report from the AAPM Working Group for the Development of a Research Database (WGDRD). Medical Physics, 44(4), 1590-1601. [More Information]
  • Feain, I., Court, L., Palta, J., Beddar, S., Keall, P. (2017). Innovations in radiotherapy technology. Clinical Oncology, 29(2), 120-128. [More Information]
  • Kim, J., Nguyen, D., Huang, C., Fuangrod, T., Caillet, V., O’Brien, R., Poulsen, P., Booth, J., Keall, P. (2017). Quantifying the accuracy and precision of a novel real-time 6 degree-of-freedom kilovoltage intrafraction monitoring (KIM) target tracking system. Physics in Medicine and Biology, 62(14), 5744-5759. [More Information]
  • Woodruff, H., Shieh, C., Hegi-Johnson, F., Keall, P., Kipritidis, J. (2017). Quantifying the reproducibility of lung ventilation images between 4-Dimensional Cone Beam CT and 4-Dimensional CT. Medical Physics, 44(5), 1771-1781. [More Information]
  • O’Brien, R., Stankovic, U., Sonke, J., Keall, P. (2017). Reducing 4DCBCT imaging time and dose: The first implementation of variable gantry speed 4DCBCT on a linear accelerator. Physics in Medicine and Biology, 62(11), 4300-4317. [More Information]
  • Nguyen, D., O’Brien, R., Kim, J., Huang, C., Wilton, L., Greer, P., Legge, K., Booth, J., Poulsen, P., Martin, J., Keall, P. (2017). The first clinical implementation of a real-time six degree of freedom target tracking system during radiation therapy based on Kilovoltage Intrafraction Monitoring (KIM). Radiotherapy and Oncology, 123(1), 37-42. [More Information]
  • Rai, R., Kumar, S., Batumalai, V., Elwadia, D., Ohanessian, L., Juresic, E., Cassapi, L., Vinod, S., Holloway, L., Keall, P., et al (2017). The integration of MRI in radiation therapy: collaboration of radiographers and radiation therapists. Journal of Medical Radiation Sciences, 64(1), 61-68. [More Information]

2016

  • Colvill, E., Booth, J., Nill, S., Fast, M., Bedford, J., Oelfke, U., Nakamura, M., Poulsen, P., Worm, E., Hansen, R., Keall, P., et al (2016). A dosimetric comparison of real-time adaptive and non-adaptive radiotherapy: A multi-institutional study encompassing robotic, gimbaled, multileaf collimator and couch tracking. Radiotherapy and Oncology, 119(1), 159-165. [More Information]
  • Whelan, B., Gierman, S., Holloway, L., Schmerge, J., Keall, P., Fahrig, R. (2016). A novel electron accelerator for MRI-Linac radiotherapy. Medical Physics, 43(3), 1285-1294. [More Information]
  • Zwan, B., Barnes, M., Fuangrod, T., Stanton, C., O’Connor, D., Keall, P., Greer, P. (2016). An EPID-based system for gantry-resolved MLC quality assurance for VMAT. Journal of Applied Clinical Medical Physics, 17(5), 348-365. [More Information]
  • Lee, D., Greer, P., Ludbrook, J., Arm, J., Hunter, P., Pollock, S., Makhija, K., O’Brien, R., Kim, T., Keall, P. (2016). Audiovisual Biofeedback Improves Cine-Magnetic Resonance Imaging Measured Lung Tumor Motion Consistency. International Journal of Radiation Oncology: Biology Physics, 94(3), 628-636. [More Information]
  • Kida, S., Bal, M., Kabus, S., Negahdar, M., Shan, X., Loo Jr, B., Keall, P., Yamamoto, T. (2016). CT ventilation functional image-based IMRT treatment plans are comparable to SPECT ventilation functional image-based plans. Radiotherapy and Oncology, 118(3), 521-527. [More Information]
  • Osborn, B., Ge, Y., Hardcastle, N., Metcalfe, P., Keall, P. (2016). Dose enhancement in radiotherapy of small lung tumors using inline magnetic fields: A Monte Carlo based planning study. Medical Physics, 43(1), 368-377. [More Information]
  • Kipritidis, J., Hofman, M., Siva, S., Callahan, J., Le Roux, P., Woodruff, H., Counter, W., Keall, P. (2016). Estimating lung ventilation directly from 4D CT Hounsfield unit values. Medical Physics, 43(1), 33-43. [More Information]
  • Feain, I., Shieh, C., White, P., O’Brien, R., Fisher, S., Counter, W., Lazarakis, P., Stewart, D., Downes, S., Jackson, M., Whelan, B., Makhija, K., Huang, C., Keall, P., et al (2016). Functional imaging equivalence and proof of concept for image-guided adaptive radiotherapy with fixed gantry and rotating couch. Advances in Radiation Oncology, 1(4), 365-372. [More Information]
  • Eslick, E., Bailey, D., Harris, B., Kipritidis, J., Stevens, M., Li, B., Bailey, E., Gradinscak, D., Pollock, S., Htun, C., Keall, P., et al (2016). Measurement of preoperative lobar lung function with computed tomography ventilation imaging: progress towards rapid stratification of lung cancer lobectomy patients with abnormal lung function. European Journal Of Cardio-Thoracic Surgery, 49(4), 1075-1082. [More Information]
  • Keall, P., O’Brien, R., Cooper, B., Lu, J., Williamson, J. (2016). Optimising RMG-4DCBCT Image Acquisition. Patent No. 201280037958. China.
  • Seregni, M., Paganelli, C., Lee, D., Greer, P., Baroni, G., Keall, P., Riboldi, M. (2016). Motion prediction in MRI-guided radiotherapy based on interleaved orthogonal cine-MRI. Physics in Medicine and Biology, 61(2), 872-887. [More Information]
  • Kipritidis, J., Woodruff, H., Eslick, E., Hegi-Johnson, F., Keall, P. (2016). New pathways for end-to-end validation of CT ventilation imaging (CTVI) using deformable image registration. 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI): From Nano to Macro, Piscataway: (IEEE) Institute of Electrical and Electronics Engineers. [More Information]
  • Ipsen, S., Bruder, R., O’Brien, R., Keall, P., Schweikard, A., Poulsen, P. (2016). Online 4D ultrasound guidance for real-time motion compensation by MLC tracking. Medical Physics, 43(10), 5695-5704. [More Information]
  • Whelan, B., Holloway, L., Constantin, D., Oborn, B., Bazalova-Carter, M., Fahrig, R., Keall, P. (2016). Performance of a clinical gridded electron gun in magnetic fields: Implications for MRI-linac therapy. Medical Physics, 43(11), 5903-5914. [More Information]
  • Lee, D., Greer, P., Pollock, S., Kim, T., Keall, P. (2016). Quantifying the accuracy of the tumor motion and area as a function of acceleration factor for the simulation of the dynamic keyhole magnetic resonance imaging method. Medical Physics, 43(5), 2639-2648. [More Information]
  • Keall, P., Ng, J., Juneja, P., O’Brien, R., Huang, C., Colvill, E., Caillet, V., Simpson, E., Poulsen, P., Kneebone, A., Eade, T., Booth, J. (2016). Real-Time 3D Image Guidance Using a Standard LINAC: Measured Motion, Accuracy, and Precision of the First Prospective Clinical Trial of Kilovoltage Intrafraction Monitoringe-Guided Gating for Prostate Cancer Radiation Therapy. International Journal of Radiation Oncology: Biology Physics, 94(5), 1015-1021. [More Information]
  • Chung, H., Poulsen, P., Keall, P., Cho, S., Cho, B. (2016). Reconstruction of implanted marker trajectories from cone-beam CT projection images using interdimensional correlation modeling. Medical Physics, 43(8), 4643-4654. [More Information]
  • Wisotzky, E., O’Brien, R., Keall, P. (2016). Technical Note: A novel leaf sequencing optimization algorithm which considers previous underdose and overdose events for MLC tracking radiotherapy. Medical Physics, 43(1), 132-136. [More Information]
  • Liney, G., Dong, B., Begg, J., Vial, P., Zhang, K., Lee, F., Walker, A., Rai, R., Causer, T., Alnaghy, S., Holloway, L., Keall, P., et al (2016). Technical Note: Experimental results from a prototype high-field inline MRI-linac. Medical Physics, 43(9), 5188-5194. [More Information]
  • O’Brien, R., Cooper, B., Shieh, C., Stankovic, U., Keall, P., Sonke, J. (2016). The first implementation of respiratory triggered 4DCBCT on a linear accelerator. Physics in Medicine and Biology, 61(9), 3488-3499. [More Information]
  • Yamamoto, T., Kabus, S., Bal, M., Keall, P., Benedict, S., Daly, M. (2016). The first patient treatment of computed tomography ventilation functional image-guided radiotherapy for lung cancer. Radiotherapy and Oncology, 118(2), 227-231. [More Information]
  • Booth, J., Caillet, V., Hardcastle, N., O’Brien, R., Szymura, K., Crasta, C., Harris, B., Haddad, C., Eade, T., Keall, P. (2016). The first patient treatment of electromagnetic-guided real time adaptive radiotherapy using MLC tracking for lung SABR. Radiotherapy and Oncology, 121(1), 19-25. [More Information]
  • Yang, J., Yamamoto, T., Pollock, S., Berger, J., Diehn, M., Graves, E., Loo Jr, B., Keall, P. (2016). The impact of audiovisual biofeedback on 4D functional and anatomic imaging: Results of a lung cancer pilot study. Radiotherapy and Oncology, 120(2), 267-272. [More Information]
  • Pollock, S., Kipritidis, J., Lee, D., Bernatowicz, K., Keall, P. (2016). The impact of breathing guidance and prospective gating during thoracic 4DCT imaging: An XCAT study utilizing lung cancer patient motion. Physics in Medicine and Biology, 61(17), 6485-6501. [More Information]
  • Ipsen, S., Blanck, O., Lowther, N., Liney, G., Rai, R., Bode, F., Dunst, J., Schweikard, A., Keall, P. (2016). Towards real-time MRI-guided 3D localization of deforming targets for non-invasive cardiac radiosurgery. Physics in Medicine and Biology, 61(22), 7848-7863. [More Information]

2015

  • Pollock, S., O’Brien, R., Makhija, K., Hegi-Johnson, F., Ludbrook, J., Rezo, A., Tse, R., Eade, T., Yeghiaian-Alvandi, R., Gebski, V., Keall, P. (2015). Audiovisual biofeedback breathing guidance for lung cancer patients receiving radiotherapy: A multi-institutional phase II randomised clinical trial. BMC Cancer, 15(1), 1-8. [More Information]
  • Pollock, S., Keall, R., Keall, P. (2015). Breathing guidance in radiation oncology and radiology: A systematic review of patient and healthy volunteer studies. Medical Physics, 42(9), 5490-5509. [More Information]
  • Wallace, D., Ng, J., Keall, P., O’Brien, R., Poulsen, P., Juneja, P., Booth, J. (2015). Determining appropriate imaging parameters for kilovoltage intrafraction monitoring: an experimental phantom study. Physics in Medicine and Biology, 60(12), 4835-4847. [More Information]
  • Pollock, S., Tse, R., Martin, D., McLean, L., Cho, G., Hill, R., Pickard, S., Aston, P., Huang, C., Makhija, K., O’Brien, R., Keall, P. (2015). First clinical implementation of audiovisual biofeedback in liver cancer stereotactic body radiation therapy. Journal of Medical Imaging and Radiation Oncology, 59(5), 654-656. [More Information]
  • Shieh, C., Kipritidis, J., O’Brien, R., Cooper, B., Kuncic, Z., Keall, P. (2015). Improving thoracic four-dimensional cone-beam CT reconstruction with anatomical-adaptive image regularization (AAIR). Physics in Medicine and Biology, 60(2), 841-868. [More Information]
  • Petasecca, M., Newall, M., Booth, J., Duncan, M., Aldosari, A., Fuduli, I., Espinoza, A., Porumb, C., Guatelli, S., Metcalfe, P., Colvill, E., Keall, P., et al (2015). MagicPlate-512: A 2D silicon detector array for quality assurance of stereotactic motion adaptive radiotherapy. Medical Physics, 42(6), 2992-3004. [More Information]
  • Shieh, C., Keall, P., Kuncic, Z., Huang, C., Feain, I. (2015). Markerless tumor tracking using short kilovoltage imaging arcs for lung image-guided radiotherapy. Physics in Medicine and Biology, 60(24), 9437-9454. [More Information]
  • Kipritidis, J., Hugo, G., Weiss, E., Williamson, J., Keall, P. (2015). Measuring interfraction and intrafraction lung function changes during radiation therapy using four-dimensional cone beam CT ventilation imaging. Medical Physics, 42(3), 1255-1267. [More Information]
  • Ruan, D., Keall, P., Sawant, A. (2015). Method and System for Real-Time DMLC-based Target tracking with Optimal Motion Compensating Leaf Adaptation S09-154. Patent No. 8971489.
  • Colvill, E., Booth, J., O’Brien, R., Eade, T., Kneebone, A., Poulsen, P., Keall, P. (2015). Multileaf Collimator Tracking Improves Dose Delivery for Prostate Cancer Radiation Therapy: Results of the First Clinical Trial. International Journal of Radiation Oncology: Biology Physics, 92(5), 1141-1147. [More Information]
  • Juneja, P., Kneebone, A., Booth, J., Thwaites, D., Kaur, R., Colvill, E., Ng, J., Keall, P., Eade, T. (2015). Prostate motion during radiotherapy of prostate cancer patients with and without application of a hydrogel spacer: a comparative study. Radiation Oncology, 10, 1-6. [More Information]
  • Oborn, B., Dowdell, S., Metcalfe, P., Crozier, S., Mohan, R., Keall, P. (2015). Proton beam deflection in MRI fields: Implications for MRI-guided proton therapy. Medical Physics, 42(5), 2113-2124. [More Information]
  • Paganelli, C., Lee, D., Greer, P., Baroni, G., Riboldi, M., Keall, P. (2015). Quantification of lung tumor rotation with automated landmark extraction using orthogonal cine MRI images. Physics in Medicine and Biology, 60(18), 7165-7178. [More Information]
  • Cooper, B., O’Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2015). Quantifying the image quality and dose reduction of respiratory triggered 4D cone-beam computed tomography with patient-measured breathing. Physics in Medicine and Biology, 60(24), 9493-9513. [More Information]
  • Bernatowicz, K., Keall, P., Mishra, P., Knopf, A., Lomax, A., Kipritidis, J. (2015). Quantifying the impact of respiratory-gated 4D CT acquisition on thoracic image quality: a digital phantom study. Medical Physics, 42(1), 324-334. [More Information]
  • Huang, C., Nasehi Tehrani, J., Ng, J., Booth, J., Keall, P. (2015). Six Degrees-of-Freedom Prostate and Lung Tumor Motion Measurements Using Kilovoltage Intrafraction Monitoring. International Journal of Radiation Oncology: Biology Physics, 91(2), 368-375. [More Information]
  • Ge, Y., Booth, J., Colvill, E., O’Brien, R., Keall, P. (2015). SU-E-J-57: First Development of Adapting to Intrafraction Relative Motion Between Prostate and Pelvic Lymph Nodes Targets. Medical Physics, 42(6), 3276. [More Information]
  • Keall, P., Ng, J., O’Brien, R., Colvill, E., Huang, C., Poulsen, P., Flederlius, W., Juneja, P., Simpson, E., Bell, L., Booth, J., et al (2015). The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method. Medical Physics, 42(1), 354-358. [More Information]
  • Eslick, E., Keall, P. (2015). The Nano-X Linear Accelerator: A Compact and Economical Cancer Radiotherapy System Incorporating Patient Rotation. Technology in Cancer Research and Treatment, 14(5), 565-572. [More Information]
  • Shieh, C., Huang, C., Keall, P., Feain, I. (2015). WE-AB-303-08: Direct Lung Tumor Tracking Using Short Imaging Arcs. Medical Physics, 42(6), 3657. [More Information]
  • Oborn, B., Ge, Y., Hardcastle, N., Metcalfe, P., Keall, P. (2015). WE-G-BRD-05: Inline Magnetic Fields Enhance Tumor Dose for Small Lung Cancers. Medical Physics, 42(6), 3689. [More Information]

2014

  • Constantin, D., Holloway, L., Keall, P., Fahrig, R. (2014). A novel electron gun for inline MRI-linac configurations. Medical Physics, 41(2), 1-10. [More Information]
  • Lee, D., Greer, P., Arm, J., Keall, P., Kim, T. (2014). Audiovisual biofeedback improves image quality and reduces scan time for respiratory-gated 3D MRI. Journal of Physics: Conference Series, 489(1), 1-4. [More Information]
  • Colvill, E., Poulsen, P., Booth, J., O’Brien, R., Ng, J., Keall, P. (2014). DMLC tracking and gating can improve dose coverage for prostate VMAT. Medical Physics, 41(9), 1-10. [More Information]
  • Lee, D., Pollock, S., Whelan, B., Keall, P., Kim, T. (2014). Dynamic keyhole: A novel method to improve MR images in the presence of respiratory motion for real-time MRI. Medical Physics, 41(7), 1-8. [More Information]
  • Oborn, B., Kolling, S., Metcalfe, P., Crozier, S., Litzenberg, D., Keall, P. (2014). Electron contamination modeling and reduction in a 1 T open bore inline MRI-linac system. Medical Physics, 41(5), 051708-1-051708-15. [More Information]
  • Ravkilde, T., Keall, P., Grau, C., Hoyer, M., Poulsen, P. (2014). Fast motion-including dose error reconstruction for VMAT with and without MLC tracking. Physics in Medicine and Biology, 59(23), 7279-7296. [More Information]
  • Shieh, C., Kipritidis, J., O’Brien, R., Kuncic, Z., Keall, P. (2014). Image quality in thoracic 4D cone-beam CT: a sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing. Medical Physics, 41(4), 041912-1-041912-18. [More Information]
  • Suh, Y., Murray, W., Keall, P. (2014). IMRT Treatment Planning on 4D Geometries for the Era of Dynamic MLC Tracking. Technology in Cancer Research and Treatment, 13(6), 505-515. [More Information]
  • Sawant, A., Keall, P., Butts Pauly, K., Alley, M., Vasanawala, S., Loo, B., Hinkle, J., Joshi, S. (2014). Investigating the feasibility of rapid MRI for image-guided motion management in lung cancer radiotherapy. BioMed Research International, 2014, 1-7. [More Information]
  • Kolling, S., Oborn, B., Keall, P., Horvat, J. (2014). Magnetization curves of sintered heavy tungsten alloys for applications in MRI-guided radiotherapy. Medical Physics, 41(6), 061707-1-061707-6. [More Information]
  • Falk, M., Pommer, T., Keall, P., Korreman, S., Persson, G., Poulsen, P., af Rosenschold, P. (2014). Motion management during IMAT treatment of mobile lung tumors-A comparison of MLC tracking and gated delivery. Medical Physics, 41(10), 1-8. [More Information]
  • Kim, T., Kim, S., Park, Y., Youn, K., Keall, P., Lee, R. (2014). Motion management within two respiratory-gating windows: feasibility study of dual quasi-breath-hold technique in gated medical procedures. Physics in Medicine and Biology, 59(21), 6583-6594. [More Information]

 

  • O’Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2014). Optimizing 4DCBCT projection allocation to respiratory bins. Physics in Medicine and Biology, 59(19), 5631-5649. [More Information]
  • Yamamoto, T., Kabus, S., Lorenz, C., Mittra, E., Hong, J., Chung, M., Eclov, N., To, J., Diehn, M., Loo, B., Keall, P. (2014). Pulmonary Ventilation Imaging Based on 4-Dimensional Computed Tomography: Comparison With Pulmonary Function Tests and SPECT Ventilation Images. International Journal of Radiation Oncology: Biology Physics, 90(2), 414-422. [More Information]
  • Ng, J., Booth, J., O’Brien, R., Colvill, E., Huang, C., Poulsen, P., Keall, P. (2014). Quality assurance for the clinical implementation of kilovoltage intrafraction monitoring for prostate cancer VMAT. Medical Physics, 41(11), 111712-1-111712-9. [More Information]
  • Ipsen, S., Blanck, O., Oborn, B., Bode, F., Liney, G., Hunold, P., Rades, D., Schweikard, A., Keall, P. (2014). Radiotherapy beyond cancer: Target localization in real-time MRI and treatment planning for cardiac radiosurgery. Medical Physics, 41(12), 1-8. [More Information]
  • Bryant, J., Rottmann, J., Lewis, J., Mishra, P., Keall, P., Berbeco, R. (2014). Registration of clinical volumes to beams-eye-view images for real-time tracking. Medical Physics, 41(12), 1-9. [More Information]
  • O’Brien, R., Cooper, B., Kipritidis, J., Shieh, C., Keall, P. (2014). Respiratory motion guided four dimensional cone beam computed tomography: Encompassing irregular breathing. Physics in Medicine and Biology, 59(3), 579-595. [More Information]
  • Keall, P., Barton, M., Crozier, S. (2014). The Australian Magnetic Resonance Imaging-Linac Program. Seminars in Radiation Oncology, 24(3), 203-206. [More Information]
  • Keall, P., Colvill, E., O’Brien, R., Ng, J., Poulsen, P., Eade, T., Kneebone, A., Booth, J. (2014). The first clinical implementation of electromagnetic transponder-guided MLC tracking. Medical Physics, 41(2), 020702-1-020702-5. [More Information]
  • Steel, H., Pollock, S., Lee, D., Keall, P., Kim, T. (2014). The internal-external respiratory motion correlation is unaffected by audiovisual biofeedback. Australasian Physical and Engineering Sciences in Medicine, 37(1), 97-102. [More Information]
  • Yang, J., Yamamoto, T., Mazin, S., Graves, E., Keall, P. (2014). The potential of positron emission tomography for intratreatment dynamic lung tumor tracking: a phantom study. Medical Physics, 41(2), 021718-1-021718-14. [ More Information]
  • Ge, Y., O’Brien, R., Shieh, C., Booth, J., Keall, P. (2014). Toward the development of intrafraction tumor deformation tracking using a dynamic multi-leaf collimator. Medical Physics, 41(6), 061703-1-061703-10. [More Information]
  • Kipritidis, J., Siva, S., Hofman, M., Callahan, J., Hicks, R., Keall, P. (2014). Validating and improving CT ventilation imaging by correlating with ventilation 4D-PET/CT using 68Ga-labeled nanoparticles. Medical Physics, 41(1), 011910-1-011910-12. [More Information]

2013

  • Yamamoto, T., Kabus, S., Lorenz, C., Johnston, E., Maxim, P., Diehn, M., Eclov, N., Barquero, C., Loo, Jr., B., Keall, P. (2013). 4D CT lung ventilation images are affected by the 4D CT sorting method. Medical Physics, 40(10), 1-9. [More Information]
  • Pollock, S., Lee, D., Keall, P., Kim, T. (2013). Audiovisual biofeedback improves motion prediction accuracy. Medical Physics, 40(4), 041705-1-041705-9. [More Information]
  • Pommer, T., Falk, M., Poulsen, P., Keall, P., O’Brien, R., Petersen, P., af Rosenschold, P. (2013). Dosimetric benefit of DMLC tracking for conventional and sub-volume boosted prostate intensity-modulated arc radiotherapy. Physics in Medicine and Biology, 58(7), 2349-2361. [More Information]
  • Ng, J., Booth, J., Poulsen, P., Kuncic, Z., Keall, P. (2013). Estimation of effective imaging dose for kilovoltage intratreatment monitoring of the prostate position during cancer radiotherapy. Physics in Medicine and Biology, 58(17), 5983-5996. [More Information]
  • Balik, S., Weiss, E., Jan, N., Roman, N., Sleeman, W., Fatyga, M., Christensen, G., Zhang, C., Murphy, M., Lu, J., Keall, P., et al (2013). Evaluation of 4-dimensional Computed Tomography to 4-dimensional Cone-Beam Computed Tomography Deformable Image Registration for Lung Cancer Adaptive Radiation Therapy. International Journal of Radiation: Oncology – Biology – Physics, 86(2), 372-379. [More Information]
  • Kolling, S., Oborn, B., Keall, P. (2013). Impact of the MLC on the MRI field distortion of a prototype MRI-linac. Medical Physics, 40(12), 121705-1-121705-10. [More Information]
  • Rottman, J., Keall, P., Berbeco, R. (2013). Markerless EPID image guided dynamic multi-leaf collimator tracking for lung tumors. Physics in Medicine and Biology, 58(12), 4195-4204. [More Information]
  • O’Brien, R., Cooper, B., Keall, P. (2013). Optimizing 4D cone beam computed tomography acquisition by varying the gantry velocity and projection time interval. Physics in Medicine and Biology, 58(6), 1705-1723. [More Information]
  • Nasehi Tehrani, J., O’Brien, R., Poulsen, P., Keall, P. (2013). Real-time estimation of prostate tumor rotation and translation with a kV imaging system based on an iterative closest point algorithm. Physics in Medicine and Biology, 58(23), 8517-8533. [More Information]
  • Rottmann, J., Keall, P., Berbeco, R. (2013). Real-time soft tissue motion estimation for lung tumors during radiotherapy delivery. Medical Physics, 40(9), 091713-1-091713-7. [More Information]
  • Cooper, B., O’Brien, R., Balik, S., Hugo, G., Keall, P. (2013). Respiratory triggered 4D cone-beam computed tomography: A novel method to reduce imaging dose. Medical Physics, 40(4), 041901-1-041901-9. [More Information]
  • Pommer, T., Falk, M., Poulsen, P., Keall, P., O’Brien, R., af Rosenschold, P. (2013). The impact of leaf width and plan complexity on DMLC tracking of prostate intensity modulated arc therapy. Medical Physics, 40(11), 111717-1-111717-6. [More Information]
  • Bjerre, T., Crijns, S., af Rosenschold, P., Aznar, M., Specht, L., Larsen, R., Keall, P. (2013). Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes. Physics in Medicine and Biology, 58(14), 4943-4950. [More Information]
  • Ravkilde, T., Keall, P., Grau, C., Hoyer, M., Poulsen, P. (2013). Time-resolved dose distributions to moving targets during volumetric modulated arc therapy with and without dynamic MLC tracking. Medical Physics, 40(11), 111723-1-111723-8. [More Information]
  • Ravkilde, T., Keall, P., Grau, C., Hoyer, M., Poulsen, P. (2013). Time-resolved dose reconstruction by motion encoding of volumetric modulated arc therapy fields delivered with and without dynamic multi-leaf collimator tracking. Acta Oncologica, 52(7), 1497-1503. [More Information]

2012

  • Poulsen, P., Schmidt, M., Keall, P., Worm, E., Fledelius, W., Hoffmann, L. (2012). A method of dose reconstruction for moving targets compatible with dynamic treatments. Medical Physics, 39(10), 6237-6246. [More Information]
  • Kim, T., Pollock, S., Lee, D., O’Brien, R., Keall, P. (2012). Audiovisual biofeedback improves diaphragm motion reproducibility in MRI. Medical Physics, 39(11), 6921-6928. [More Information]
  • Wu, J., Ruan, D., Cho, B., Sawant, A., Petersen, J., Newell, L., Cattell, H., Keall, P. (2012). Electromagnetic Detection and Real-Time DMLC Adaptation to Target Rotation During Radiotherapy. International Journal of Radiation: Oncology – Biology – Physics, 82(3), e545-e553. [More Information]
  • Oborn, B., Metcalfe, P., Butson, M., Rosenfeld, A., Keall, P. (2012). Electron contamination modeling and skin dose in 6 MV longitudinal field MRIgRT: Impact of the MRI and MRI fringe field. Medical Physics, 39(2), 874-890. [More Information]
  • Cho, B., Poulsen, P., Ruan, D., Sawant, A., Keall, P. (2012). Experimental investigation of a general real-time 3D target localization method using sequential kV imaging combined with respiratory monitoring. Physics in Medicine and Biology, 57(22), 7395-7407. [More Information]
  • Poulsen, P., Fledelius, W., Cho, B., Keall, P. (2012). Image-Based Dynamic Multileaf Collimator Tracking of Moving Targets During Intensity-Modulated Arc Therapy. International Journal of Radiation: Oncology – Biology – Physics, 83(2), e265-e271. [More Information]
  • Ng, J., Booth, J., Poulsen, P., Fledelius, W., Worm, E., Eade, T., Hegi-Johnson, F., Kneebone, A., Kuncic, Z., Keall, P. (2012). Kilovoltage intrafraction monitoring for prostate intensity modulated arc therapy: First clinical results. International Journal of Radiation: Oncology – Biology – Physics, 84(5), e655-e661. [More Information]
  • Crocker, J., Ng, J., Keall, P., Booth, J. (2012). Measurement of patient imaging dose for real-time kilovoltage x-ray intrafraction tumour position monitoring in prostate patients. Physics in Medicine and Biology, 57(10), 2969-2980. [More Information]
  • Poulsen, P., Carl, J., Nielsen, J., Nielsen, M., Thomsen, J., Jensen, H., Kjaergaard, B., Zepernick, P., Worm, E., Fledelius, W., Keall, P., et al (2012). Megavoltage Image-Based Dynamic Multileaf Collimator Tracking of a NiTi Stent in Porcine Lungs on a Linear Accelerator. International Journal of Radiation: Oncology – Biology – Physics, 82(2), e321-e327. [More Information]
  • Yamamoto, T., Kabus, S., von Berg, J., Lorenz, C., Chung, M., Hong, J., Loo, B., Keall, P. (2012). Reproducibility of four-dimensional computed tomography-based lung ventilation imaging. Academic Radiology, 19(12), 1554-1565. [More Information]
  • Falk, M., Larsson, T., Keall, P., Chul Cho, B., Aznar, M., Korreman, S., Poulsen, P., af Rosenschold, P. (2012). The dosimetric impact of inversely optimized arc radiotherapy plan modulation for real-time dynamic MLC tracking delivery. Medical Physics, 39(3), 1588-1594. [More Information]
  • Yang, J., Yamamoto, T., Cho, B., Seo, Y., Keall, P. (2012). The impact of audio-visual biofeedback on 4D PET images: Results of a phantom study. Medical Physics, 39(2), 1046-1057. [More Information]

2011

  • Poulsen, P., Fledelius, W., Keall, P., Weiss, E., Lu, J., Brackbill, E., Hugo, G. (2011). A method for robust segmentation of arbitrarily shaped radiopaque structures in cone-beam CT projections. Medical Physics, 38(4), 2151-2156. [More Information]
  • Constantin, D., Fahrig, R., Keall, P. (2011). A study of the effect of in-line and perpendicular magnetic fields on beam characteristics of electron guns in medical linear accelerators. Medical Physics, 38(7), 4174-4185. [More Information]
  • Ruan, D., Keall, P. (2011). Dynamic multileaf collimator control for motion adaptive radiotherapy: an optimization approach. 2011 IEEE Power Engineering and Automation Conference (PEAM 2011), Piscataway, New Jersey, United States of America: (IEEE) Institute of Electrical and Electronics Engineers. [More Information]
  • Keall, P., Sawant, A., Cho, B., Ruan, D., Wu, J., Poulsen, P., Petersen, J., Newell, L., Cattell, H., Korreman, S. (2011). Electromagnetic-Guided Dynamic Multileaf Collimator Tracking Enables Motion Management for Intensity-Modulated Arc Therapy. International Journal of Radiation: Oncology – Biology – Physics, 79(1), 312-320. [More Information]
  • Yoon, J., Sawant, A., Suh, Y., Cho, B., Suh, T., Keall, P. (2011). Experimental investigation of a moving averaging algorithm for motion perpendicular to the leaf travel direction in dynamic MLC target tracking. Medical Physics, 38(7), 3924-3931. [More Information]
  • Yamamoto, T., Kabus, S., Klinder, T., von Berg, J., Lorenz, C., Loo, Jr., B., Keall, P. (2011). Four-dimensional computed tomography pulmonary ventilation images vary with deformable image registration algorithms and metrics. Medical Physics, 38(3), 1348-1358. [More Information]
  • Ravkilde, T., Keall, P., Hojbjerre, K., Fledelius, W., Worm, E., Poulsen, P. (2011). Geometric accuracy of dynamic MLC tracking with an implantable wired electromagnetic transponder. Acta Oncologica, 50(6), 944-951. [More Information]
  • Carlson, D., Keall, P., Loo, B., Chen, Z., Brown, J. (2011). Hypofractionation results in reduced tumor cell kill compared to conventional fractionation for tumors with regions of hypoxia. International Journal of Radiation: Oncology – Biology – Physics, 79(4), 1188-1195. [More Information]
  • Yamamoto, T., Kabus, S., von Berg, J., Lorenz, C., Keall, P. (2011). Impact of Four-Dimensional Computed Tomography Pulmonary Ventilation Imaging-Based Functional Avoidance for Lung Cancer Radiotherapy. International Journal of Radiation: Oncology – Biology – Physics, 79(1), 279-288. [More Information]
  • Yamamoto, T., Kabus, S., Klinder, T., Lorenz, C., von Berg, J., Blaffert, T., Loo Jr, B., Keall, P. (2011). Investigation of four-dimensional computed tomography-based pulmonary ventilation imaging in patients with emphysematous lung regions. Physics in Medicine and Biology, 56(7), 2279-2298. [More Information]
  • Keall, P. (2011). Locating and targeting moving tumors with radiation beams. Frontiers of Radiation Therapy and Oncology, 43, 118-131. [More Information]
  • Constantin, M., Perl, J., LoSasso, T., Salop, A., Whittum, D., Narula, A., Svatos, M., Keall, P. (2011). Modeling the truebeam linac using a CAD to Geant4 geometry implementation: dose and IAEA-compliant phase space calculations. Medical Physics, 38(7), 4018-4024. [More Information]
  • Cho, B., Poulsen, P., Sawant, A., Ruan, D., Keall, P. (2011). Real-Time Target Position Estimation Using Stereoscopic Kilovoltage/Megavoltage Imaging and External Respiratory Monitoring for Dynamic Multileaf Collimator Tracking. International Journal of Radiation: Oncology – Biology – Physics, 79(1), 269-278. [More Information]
  • Fledelius, W., Keall, P., Cho, B., Yang, X., Morf, D., Scheib, S., Poulsen, P. (2011). Tracking latency in image-based dynamic MLC tracking with direct image access. Acta Oncologica, 50(6), 952-959. [More Information]

2010

  • Zhou, H., Rodriguez, M., Van Den Haak, F., Nelson, G., Jogani, R., Xu, J., Zhu, X., Xian, Y., Tran, P., Felsher, D., Keall, P., et al (2010). Development of a Micro-Computed Tomography-Based Image-Guided Conformal Radiotherapy System for Small Animals. International Journal of Radiation: Oncology – Biology – Physics, 78(1), 297-305. [More Information]
  • Poulsen, P., Cho, B., Ruan, D., Sawant, A., Keall, P. (2010). Dynamic Multileaf Collimator Tracking of Respiratory Target Motion Based on a Single Kilovoltage Imager During Arc Radiotherapy. International Journal of Radiation: Oncology – Biology – Physics, 77(2), 600-607. [More Information]
  • Poulsen, P., Cho, B., Sawant, A., Keall, P. (2010). Implementation of a new method for dynamic multileaf collimator tracking of prostate motion in arc radiotherapy using a single kV imager. International Journal of Radiation: Oncology – Biology – Physics, 76(3), 914-923. [More Information]
  • Motomura, A., Bazalova, M., Zhou, H., Keall, P., Graves, E. (2010). Investigation of the effects of treatment planning variables in small animal radiotherapy dose distributions. Medical Physics, 37(2), 590-599. [More Information]
  • Constantin, M., Constantin, D., Keall, P., Narula, A., Svatos, M., Perl, J. (2010). Linking computer-aided design (CAD) to Geant4-based Monte Carlo simulations for precise implementation of complex treatment head geometries. Physics in Medicine and Biology, 55(8), N211-N220. [More Information]
  • Ruan, D., Keall, P. (2010). Online prediction of respiratory motion: multidimensional processing with low-dimensional feature learning. Physics in Medicine and Biology, 55(11), 3011-3025. [More Information]
  • Langner, U., Keall, P. (2010). Quantification of artifact reduction with real-time cine four-dimensional computed tomography acquisition methods. International Journal of Radiation: Oncology – Biology – Physics, 76(4), 1242-1250. [More Information]
  • Falk, M., af Rosenschold, P., Keall, P., Cho, B., Poulsen, P., Povzner, S., Sawant, A., Zimmerman, J., Korreman, S. (2010). Real-time dynamic MLC tracking for inversely optimized arc radiotherapy. Radiotherapy and Oncology, 94(2), 218-223. [More Information]
  • Cho, B., Poulsen, P., Keall, P. (2010). Real-time tumor tracking using sequential kV imaging combined with respiratory monitoring: a general framework applicable to commonly used IGRT systems. Physics in Medicine and Biology, 55(12), 3299-3316. [More Information]