The University of Sydney  - Home

VENTURE: Ventilation using radiographic examination

A pilot study to compare functional lung imaging techniques for the reduction of toxicity in functional avoidance radiotherapy

The goal of this observational validation study is to determine the best implementation of fluoroscopic and CT ventilation imaging in patients having non-stereotactic ablative body radiotherapy (non-SABR) radiotherapy for stages II-IV lung cancer. The main questions it aims to answer are:

  • Assess the dosimetric variation in functional avoidance radiation therapy (RT) plans produced using these ventilation imaging techniques,
  • Establish a quality assurance procedure for functional lung avoidance radiation therapy, and
  • Evaluate the clinical acceptable thresholds for accuracy of the method.

Trial information: https://clinicaltrials.gov/study/NCT06159660