Image X Institute Research Projects

With the commencement of the National Lung Cancer Screening program the number ofdiagnostic biopsies is likely to increase. A new collaboration with Dr Tess Reynolds and DrNicholas Hindley with pulmonologists from Royal Prince Alfred Hospital and other Australianhospitals aims to extend the capabilities of CBCT platforms to improve diagnostic yield forCBCT-guided procedures. Innovations such as…

Surgical Guides Accurate drilling and cutting are fundamental to successful and efficient surgical procedures. 3D-printed surgical guides are increasingly being used clinically to complement surgeon experience, allowing pre-planning of drilling and cutting that takes into consideration individual anatomical characteristics. To date, 3D-printed surgical guides have been predominately developed from preoperative CT and MRI scans. Working…

Image X Interventional Imaging is an international academic-industry-healthcare program led by Dr Tess Reynolds. It is dedicated to delivering innovative robotic imaging and novel 3D-printed solutions to aid in the diagnosis and treatment of disease spanning cardiology, neurology, oncology, radiology, and orthopaedics. Project highlights Extending the intraoperative field-of-view Intraoperative 3D Cone Beam CT (CBCT) imaging…

The problem to be solved Lung cancer is the leading cause of cancer death worldwide. Better targeted radiotherapy will improve treatment outcomes: a 1-Gy increase in tumour dose results in a 4% improvement in survival and a 1-Gy decrease in lung dose results in a 2% reduction in pneumonitis. To achieve tumour dose increase and…

Clearer lung cancer images, on standard CT Imagers. Current Results Milestones Intellectual property Keall, P.J. and J.F. Williamson, Method and system of adaptive control for reducing motion artifacts and patient dose in four dimensional computed tomography. 2013 Publications N. Morton, P. Keall, R. O’Brien and T. Reynolds, “CArdiac and REspiratory adaptive Computed Tomography (CARE-CT): a proof-of-concept…

Safer, Faster, Clearer Imaging. What if we adapted the imaging equipment to the moving patient, rather than making the patient conform to the limitations of the equipment? Acquiring images only when the heart and lungs are in perfect position would result in clearer images, and no unnecessary radiation dose to the patient. We’re creating imaging…

CT Ventilation Imaging is software that shows us how well different areas of the lung are performing. This means we can make sure we protect the healthy areas during radiation therapy. Cancer and lung function. For people with lung cancer, there are numerous factors other than the cancer itself which can seriously impact on the…

By connecting the patient’s physiological signals to imaging acquisition, we can ensure clearer images, lower imaging dose and faster acquisition. The Patient Connected Imaging Program is a suite of projects which use the patient’s respiratory or cardiac signals to improve the images we can achieve across different imaging techniques. REACT Clearer lung cancer images, on…

Reducing the impact of radiation on the heart for cancer and cardiac disease patients The Cardiac Radioablation program is funded by an NHMRC Synergy Grant. Background Ventricular tachycardia (VT) and atrial fibrillation (AT) are cardiac conditions that affect over 33.5 million people globally every year. Treatment typically involves invasive heart surgery to manually create scar…

AV biofeedback is a simple, personalised and interactive respiratory guide designed to facilitate regular patient breathing. The AV biofeedback system is shown in figure 1. Figure 1. AV biofeedback system. Display screen and marker block on the abdomen shown. The visual display (centre) as seen by the subject (sans arrows) of the AV biofeedback system…

Real-time cancer targeting on a standard linear accelerator. The Problem Our solution How KIM works Intellectual Property Three granted US patents Research Opportunities For more information and enquiries contact Professor Paul Keall. [email protected]

Compatible with 95% of existing radiotherapy systems, Beam Adaptation is an affordable technology that has the potential to improve the outcomes for millions of cancer patients globally. Cancer Is a Moving Target. Even when a patient is lying perfectly still, there are dynamic processes happening inside the body. The heart is beating and the lungs…

The Problem Due to a patient’s breathing, lung tumours are constantly moving. Current radiotherapy treatments allow for this movement by treating with a large radiation beam, to try and ensure they cover the entire tumour. This means that healthy tissue often gets hit with radiation and can sometimes even miss the tumour. For lung cancer…

Reducing anxiety and distress for head and neck cancer patients. Remove the Mask is a patient-led project forged by Julie McCrossin OAM and Professor Paul Keall, to improve treatment for Head and Neck Cancer (HNC) patients. The project’s first steps were enabled by a successful public crowdfunding campaign in 2018. This funding provided Remove the…